Record in detail

General Info

lamp_id:L01A000436
Name:BR1LB_RANLU
FullName:Brevinin-1Lb
Source:Rana luteiventris
Mass:2582.3 Da
Sequence Length:24 aa
Isoelectric Point:9.67
Activity:Antibacterial
Sequence
FLPMLAGLAASMVPKFVCLITKKC
Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli.

Cross-Linking

Cross-linking
1 Database:APD 462
2 Database:CAMP CAMPSQ403
3 Database:DBAASP 1802
4 Database:dbAMP dbAMP_02146
5 Database:DRAMP DRAMP02090
6 Database:SATPdb satpdb27865
7 Database:Uniprot P82826
8 Database:AMD BR1LB_RANLU

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000436 From 1 To 24 E-value: 0.00000002 Score: 49.3
FLPMLAGLAASMVPKFVCLITKKC
2. L01A000435 From 1 To 24 E-value: 0.0000001 Score: 47
FLPMLAGLAASMVPKLVCLITKKC
3. L11A013306 From 1 To 24 E-value: 0.000009 Score: 40.8
FLPILAGLAANLVPKLICSITKKC
4. L02A001723 From 1 To 24 E-value: 0.00001 Score: 40.4
FFPMLAGVAARVVPKVICLITKKC
5. L13A010541 From 1 To 24 E-value: 0.00001 Score: 40
FLPMLAGLAANFLPKIVCKITKKC

Structure

Domains
1 Name:Antimicrobial_frog_1 Interpro Link:IPR012520

Structures

Activity

Antibacterial Activities
1 Target: E. coli MIC: 41.3168 μg/ml (16 μM)
2 Target: S. aureus MIC: 20.6584 μg/ml (8 μM)

Toxicity

Toxicity

Reference

Reference
[1] Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
Journal:Eur. J. Biochem., 2000, 267, 894-900 [MEDLINE:20117700]

Comments

Comments