Record in detail

General Info

lamp_id:L01A000438
Name:BR1BB_LITBE
FullName:Brevinin-1Bb
Source:Lithobates berlandieri
Mass:2569.2 Da
Sequence Length:24 aa
Isoelectric Point:10.35
Activity:Antibacterial, Antifungal
Sequence
FLPAIAGMAAKFLPKIFCAISKKC
Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. Has activity against C.albicans.

Cross-Linking

Cross-linking
1 Database:APD 464
2 Database:CAMP CAMPSQ405
3 Database:DBAASP 1810
4 Database:dbAMP dbAMP_01967
5 Database:DRAMP DRAMP02092
6 Database:SATPdb satpdb12699
7 Database:Uniprot P82834
8 Database:AMD BR1BB_RANBE

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000438 From 1 To 24 E-value: 0.00000005 Score: 48.1
FLPAIAGMAAKFLPKIFCAISKKC
2. L01A000440 From 1 To 24 E-value: 0.0000002 Score: 46.2
FLPAIAGVAAKFLPKIFCAISKKC
3. L12A09652| From 21 To 44 E-value: 0.0000002 Score: 46.2
FLPAIVGAAAKFLPKIFCAISKKC
4. L12A09644| From 21 To 44 E-value: 0.0000003 Score: 45.8
FLPIIAGIAAKFLPKIFCAISKKC
5. L01A000437 From 1 To 24 E-value: 0.0000003 Score: 45.4
FLPFIAGMAAKFLPKIFCAISKKC

Structure

Domains
1 Name:Antimicrobial_frog_1 Interpro Link:IPR012520

Structures

Activity

Antibacterial Activities
1 Target: E. coli MIC: 7.7076 μg/ml (3 μM)
2 Target: S. aureus MIC: 2.5692 μg/ml (1 μM)

Toxicity

Toxicity

Reference

Reference
[1] Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
Journal:Eur. J. Biochem., 2000, 267, 894-900 [MEDLINE:20117700]

Comments

Comments