Record in detail


General Info

  • lamp_id:L01A000438
  • Name:BR1BB_LITBE
  • FullName:Brevinin-1Bb
  • Source:Lithobates berlandieri
  • Mass:2569.2 Da
  • Sequence Length:24 aa
  • Isoelectric Point:10.35
  • Activity:Antibacterial, Antifungal
  • Sequence
        FLPAIAGMAAKFLPKIFCAISKKC
  • Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. Has activity against C.albicans.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000438    From 1 To 24 E-value: 0.00000005 Score: 48.1
        FLPAIAGMAAKFLPKIFCAISKKC
  • 2. L01A000440    From 1 To 24 E-value: 0.0000002 Score: 46.2
        FLPAIAGVAAKFLPKIFCAISKKC
  • 3. L12A09652|    From 21 To 44 E-value: 0.0000002 Score: 46.2
        FLPAIVGAAAKFLPKIFCAISKKC
  • 4. L12A09644|    From 21 To 44 E-value: 0.0000003 Score: 45.8
        FLPIIAGIAAKFLPKIFCAISKKC
  • 5. L01A000437    From 1 To 24 E-value: 0.0000003 Score: 45.4
        FLPFIAGMAAKFLPKIFCAISKKC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_1    Interpro Link:IPR012520
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  E. coli  MIC:  7.7076 μg/ml  (3 μM)  
  •   2  Target:  S. aureus  MIC:  2.5692 μg/ml  (1 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
  •   Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
  •   Journal:Eur. J. Biochem., 2000, 267, 894-900  [MEDLINE:20117700]

Comments

  •   Comments

  •     No comments found on LAMP database



CAPTCHA Image   Reload Image
Enter Code*: