Record in detail

General Info

lamp_id:L01A000439
Name:BR1BC_LITBE
FullName:Brevinin-1Bc
Source:Lithobates berlandieri
Mass:2613.3 Da
Sequence Length:24 aa
Isoelectric Point:10.35
Activity:Antibacterial
Sequence
FLPFIAGVAAKFLPKIFCAISKKC
Function:Antibacterial activity against Gram-positive bacterium S.aureus.

Cross-Linking

Cross-linking
1 Database:APD 465
2 Database:CAMP CAMPSQ406
3 Database:DBAASP 1811
4 Database:dbAMP dbAMP_01998
5 Database:DRAMP DRAMP02093
6 Database:SATPdb satpdb19829
7 Database:Uniprot P82835
8 Database:AMD BR1BC_RANBE

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000439 From 1 To 24 E-value: 0.00000007 Score: 47.8
FLPFIAGVAAKFLPKIFCAISKKC
2. L01A000437 From 1 To 24 E-value: 0.0000001 Score: 46.6
FLPFIAGMAAKFLPKIFCAISKKC
3. L12A09644| From 21 To 44 E-value: 0.0000002 Score: 46.6
FLPIIAGIAAKFLPKIFCAISKKC
4. L01A000442 From 1 To 24 E-value: 0.0000003 Score: 45.4
FLPFIAGMAANFLPKIFCAISKKC
5. L12A09645| From 21 To 44 E-value: 0.0000004 Score: 45.4
FLPIIAGIAAKFLPKIFCTISKKC

Structure

Domains
1 Name:Antimicrobial_frog_1 Interpro Link:IPR012520

Structures

Activity

Antibacterial Activities
1 Target: S. aureus MIC: 33.9729 μg/ml (13 μM)

Toxicity

Toxicity

Reference

Reference
[1] Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
Journal:Eur. J. Biochem., 2000, 267, 894-900 [MEDLINE:20117700]

Comments

Comments