Record in detail

General Info

lamp_id:L01A000440
Name:BR1BD_LITBE
FullName:Brevinin-1Bd
Source:Lithobates berlandieri
Mass:2537.2 Da
Sequence Length:24 aa
Isoelectric Point:10.35
Activity:Antibacterial, Antifungal
Sequence
FLPAIAGVAAKFLPKIFCAISKKC
Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. Has activity against C.albicans.

Cross-Linking

Cross-linking
1 Database:APD 466
2 Database:CAMP CAMPSQ407
3 Database:DBAASP 1812
4 Database:dbAMP dbAMP_01968
5 Database:DRAMP DRAMP02094
6 Database:SATPdb satpdb17113
7 Database:Uniprot P82836
8 Database:AMD BR1BD_RANBE

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000440 From 1 To 24 E-value: 0.00000008 Score: 47.4
FLPAIAGVAAKFLPKIFCAISKKC
2. L01A000438 From 1 To 24 E-value: 0.0000002 Score: 46.2
FLPAIAGMAAKFLPKIFCAISKKC
3. L12A09652| From 21 To 44 E-value: 0.0000002 Score: 46.2
FLPAIVGAAAKFLPKIFCAISKKC
4. L12A09644| From 21 To 44 E-value: 0.0000002 Score: 46.2
FLPIIAGIAAKFLPKIFCAISKKC
5. L02A000648 From 1 To 24 E-value: 0.0000004 Score: 45.4
FLPVIAGVAAKFLPKIFCAITKKC

Structure

Domains
1 Name:Antimicrobial_frog_1 Interpro Link:IPR012520

Structures

Activity

Antibacterial Activities
1 Target: E. coli MIC: 17.7604 μg/ml (7 μM)
2 Target: S. aureus MIC: 7.6116 μg/ml (3 μM)

Toxicity

Toxicity

Reference

Reference
[1] Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
Journal:Eur. J. Biochem., 2000, 267, 894-900 [MEDLINE:20117700]

Comments

Comments