Record in detail

General Info

lamp_id:L01A000441
Name:BR1BE_LITBE
FullName:Brevinin-1Be
Source:Lithobates berlandieri
Mass:2565.2 Da
Sequence Length:24 aa
Isoelectric Point:10.35
Activity:Antibacterial
Sequence
FLPAIVGAAAKFLPKIFCVISKKC
Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli.

Cross-Linking

Cross-linking
1 Database:APD 467
2 Database:CAMP CAMPSQ408
3 Database:DBAASP 1813
4 Database:dbAMP dbAMP_01972
5 Database:DRAMP DRAMP02095
6 Database:SATPdb satpdb24406
7 Database:Uniprot P82837
8 Database:AMD BR1BE_RANBE

Top similar AMPs

Top similar AMPs on LAMP
1. L12A09652| From 21 To 44 E-value: 0.00000004 Score: 48.5
FLPAIVGAAAKFLPKIFCAISKKC
2. L01A000441 From 1 To 24 E-value: 0.00000007 Score: 47.8
FLPAIVGAAAKFLPKIFCVISKKC
3. L02A001412 From 1 To 24 E-value: 0.0000002 Score: 46.2
FLPAIVGAAAKFLPKIFCAISKKC
4. L01A000392 From 1 To 24 E-value: 0.0000005 Score: 45.1
FLPAIVGAAGKFLPKIFCAISKKC
5. L01A000391 From 1 To 24 E-value: 0.0000008 Score: 44.3
FLPAIVGAAGQFLPKIFCAISKKC

Structure

Domains
1 Name:Antimicrobial_frog_1 Interpro Link:IPR012520

Structures

Activity

Antibacterial Activities
1 Target: E. coli MIC: 38.478 μg/ml (15 μM)
2 Target: S. aureus MIC: 7.6956 μg/ml (3 μM)

Toxicity

Toxicity

Reference

Reference
[1] Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
Journal:Eur. J. Biochem., 2000, 267, 894-900 [MEDLINE:20117700]

Comments

Comments