Record in detail

General Info

lamp_id:L01A000442
Name:BR1BF_LITBE
FullName:Brevinin-1Bf
Source:Lithobates berlandieri
Mass:2631.2 Da
Sequence Length:24 aa
Isoelectric Point:9.67
Activity:Antibacterial
Sequence
FLPFIAGMAANFLPKIFCAISKKC
Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli.

Cross-Linking

Cross-linking
1 Database:APD 468
2 Database:CAMP CAMPSQ409
3 Database:DBAASP 1814
4 Database:dbAMP dbAMP_01997
5 Database:DRAMP DRAMP02096
6 Database:SATPdb satpdb25055
7 Database:Uniprot P82838
8 Database:AMD BR1BF_RANBE

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000442 From 1 To 24 E-value: 0.00000002 Score: 49.3
FLPFIAGMAANFLPKIFCAISKKC
2. L01A000437 From 1 To 24 E-value: 0.0000001 Score: 47
FLPFIAGMAAKFLPKIFCAISKKC
3. L01A003296 From 1 To 24 E-value: 0.0000003 Score: 45.8
FLPLIAGLAANFLPKIFCAITKKC
4. L01A000439 From 1 To 24 E-value: 0.0000003 Score: 45.4
FLPFIAGVAAKFLPKIFCAISKKC
5. L02A001415 From 1 To 24 E-value: 0.0000005 Score: 45.1
FLPVIAGVAANFLPKLFCAISKKC

Structure

Domains
1 Name:Antimicrobial_frog_1 Interpro Link:IPR012520

Structures

Activity

Antibacterial Activities
1 Target: E. coli MIC: 49.9928 μg/ml (19 μM)
2 Target: S. aureus MIC: 21.0496 μg/ml (8 μM)

Toxicity

Toxicity

Reference

Reference
[1] Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
Journal:Eur. J. Biochem., 2000, 267, 894-900 [MEDLINE:20117700]

Comments

Comments