Record in detail

General Info

lamp_id:L01A000443
Name:BR1PA_RANPI
FullName:Brevinin-1Pa
Source:Rana pipiens
Mass:2565.2 Da
Sequence Length:24 aa
Isoelectric Point:10.35
Activity:Antibacterial, Antifungal
Sequence
FLPIIAGVAAKVFPKIFCAISKKC
Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. Has activity against C.albicans.

Cross-Linking

Cross-linking
1 Database:APD 469
2 Database:CAMP CAMPSQ410
3 Database:DBAASP 1817
4 Database:dbAMP dbAMP_02033
5 Database:DRAMP DRAMP02097
6 Database:SATPdb satpdb16935
7 Database:Uniprot P82841
8 Database:AMD PIP_RANPI

Top similar AMPs

Top similar AMPs on LAMP
1. L12A09647| From 21 To 44 E-value: 0.00000002 Score: 49.7
FLPIIAGVAAKVFPKIFCAISKKC
2. L12A09653| From 21 To 44 E-value: 0.00000002 Score: 49.3
FLPIIAGVAAKVFPKIFCAISKKC
3. L12A07201| From 46 To 69 E-value: 0.00000005 Score: 48.1
FLPIIAGIAAKVFPKIFCAISKKC
4. L12A07202| From 47 To 70 E-value: 0.00000005 Score: 48.1
FLPIIAGIAAKVFPKIFCAISKKC
5. L12A09646| From 21 To 44 E-value: 0.00000006 Score: 47.8
FLPIIAGIAAKVFPKIFCAISKKC

Structure

Domains
1 Name:Antimicrobial_frog_1 Interpro Link:IPR012520

Structures

Activity

Antibacterial Activities
1 Target: E. coli MIC: 35.9128 μg/ml (14 μM)
2 Target: S. aureus MIC: 17.9564 μg/ml (7 μM)

Toxicity

Toxicity

Reference

Reference
[1] Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
Journal:Eur. J. Biochem., 2000, 267, 894-900 [MEDLINE:20117700]

Comments

Comments