Record in detail

General Info

lamp_id:L01A000447
Name:BR1SY_RANSY
FullName:Brevinin-1SY
Source:Rana sylvatica
Mass:2442.1 Da
Sequence Length:24 aa
Isoelectric Point:9.67
Activity:Antibacterial
Sequence
FLPVVAGLAAKVLPSIICAVTKKC
Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli.

Cross-Linking

Cross-linking
1 Database:APD 452
2 Database:CAMP CAMPSQ414
3 Database:DBAASP 1009
4 Database:dbAMP dbAMP_02171
5 Database:DRAMP DRAMP02078
6 Database:SATPdb satpdb12902
7 Database:Uniprot P82871

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000447 From 1 To 24 E-value: 0.0000001 Score: 47
FLPVVAGLAAKVLPSIICAVTKKC
2. L01A002449 From 1 To 24 E-value: 0.000003 Score: 42.4
FLPVIAGLAAKVLPKLFCAITKKC
3. L13A013879 From 1 To 24 E-value: 0.000004 Score: 42
FLPIIAGMAAKVIPSLFCAITKKC
4. L12A07358| From 47 To 70 E-value: 0.000005 Score: 41.2
FLPFIARLAAKVFPSIICSVTKKC
5. L12A09639| From 21 To 44 E-value: 0.000006 Score: 41.2
FLPIIAGVAAKVLPKLFCAITKKC

Structure

Domains
1 Name:Antimicrobial_frog_1 Interpro Link:IPR012520

Structures

Activity

Antibacterial Activities
1 Target: S.aureus MIC: 17.09 μg/ml (6.99808 μM)
2 Target: E.coli MIC: 109.89 μg/ml (44.9982 μM)

Toxicity

Toxicity

Reference

Reference
[1] Conlon J.M.,Knoop F.C.,Storey K.B.,Matutte B.,
Title:Induction of synthesis of an antimicrobial peptide in the skin of the freeze-tolerant frog, Rana sylvatica, in response to environmental stimuli.
Journal:FEBS Lett., 2000, 483, 135-138 [MEDLINE:20498923]

Comments

Comments