Record in detail
General Info
- lamp_id:L01A000448
- Name:ES2L_RANLU
- FullName:Esculentin-2L
- Source:Rana luteiventris
- Mass:3750.5 Da
- Sequence Length:37 aa
- Isoelectric Point:10.23
- Activity:Antibacterial, Antifungal
- Sequence
GILSLFTGGIKALGKTLFKMAGKAGAEHLACKATNQC - Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. Has activity against C.albicans.
Cross-Linking
- Cross-linking
- 1 Database:APD 661
- 2 Database:CAMP CAMPSQ415
- 3 Database:DBAASP 1803
- 4 Database:dbAMP dbAMP_03083
- 5 Database:DRAMP DRAMP01518
- 6 Database:SATPdb satpdb22487
- 7 Database:Uniprot P82827
- 8 Database:AMD ES2L_RANLU
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000448 From 1 To 37 E-value: 0.000000000000001 Score: 73.6
GILSLFTGGIKALGKTLFKMAGKAGAEHLACKATNQC - 2. L12A07163| From 40 To 76 E-value: 0.0000000000003 Score: 65.5
GILSLITTGAKLLGKTLFKMAGKAGAEHLACKATNQC - 3. L12A07113| From 41 To 76 E-value: 0.000000000002 Score: 63.2
IFSLLTAGAKLLGKTLFKMAGKAGAEHLACKATNQC - 4. L02A001717 From 1 To 37 E-value: 0.00000000002 Score: 59.7
GIFSALAAGVKLLGNTLFKMAGKAGAEHLACKATNQC - 5. L12A07243| From 40 To 76 E-value: 0.0000000002 Score: 55.8
GIFSLFKAGAKFFGKHLLKQAGKAGAEHLACKATNQC
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: E. coli MIC: 22.503 μg/ml (6 μM)
- 2 Target: S. aureus MIC: 11.2515 μg/ml (3 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
- Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
- Journal:Eur. J. Biochem., 2000, 267, 894-900 [MEDLINE:20117700]
Comments
- Comments
No comments found on LAMP database