Record in detail
General Info
- lamp_id:L01A000449
- Name:ES2B_LITBE
- FullName:Esculentin-2B
- Source:Lithobates berlandieri
- Mass:3837.6 Da
- Sequence Length:37 aa
- Isoelectric Point:10.51
- Activity:Antibacterial, Antifungal
- Sequence
GLFSILRGAAKFASKGLGKDLTKLGVDLVACKISKQC - Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. Has activity against C.albicans.
Cross-Linking
- Cross-linking
- 1 Database:APD 662
- 2 Database:CAMP CAMPSQ416
- 3 Database:DBAASP 1815
- 4 Database:dbAMP dbAMP_03369
- 5 Database:DRAMP DRAMP01516
- 6 Database:SATPdb satpdb15764
- 7 Database:Uniprot P82839
- 8 Database:AMD ESC2B_RANBE
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000449 From 1 To 37 E-value: 0.000000000000003 Score: 72
GLFSILRGAAKFASKGLGKDLTKLGVDLVACKISKQC - 2. L12A08200| From 4 To 40 E-value: 0.000000000002 Score: 62.8
GFSSIFRGVAKFASKGLGKDLAKLGVDLVACKISKQC - 3. L102654000 From 1 To 37 E-value: 0.000000000002 Score: 62.4
GFSSIFRGVAKFASKGLGKDLAKLGVDLVACKISKQC - 4. L12A08202| From 4 To 40 E-value: 0.000000000008 Score: 60.8
GFSSIFRGVAKFASKGLGKDLARLGVNLVACKISKQC - 5. L01A000450 From 1 To 37 E-value: 0.00000000001 Score: 60.5
GFSSIFRGVAKFASKGLGKDLARLGVNLVACKISKQC
Structure
- Domains
- 1 Name:Antimicrobial_frog_2 Interpro Link:IPR012521
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: E. coli MIC: 3.8376 μg/ml (1 μM)
- 2 Target: S. aureus MIC: 3.8376 μg/ml (1 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
- Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
- Journal:Eur. J. Biochem., 2000, 267, 894-900 [MEDLINE:20117700]
Comments
- Comments
No comments found on LAMP database