Record in detail


General Info

  • lamp_id:L01A000453
  • Name:DDSM_PHYDS
  • FullName:Dermadistinctin-M
  • Source:Phyllomedusa distincta
  • Mass:3202.8 Da
  • Sequence Length:31 aa
  • Isoelectric Point:10.8
  • Activity:Antibacterial
  • Sequence
        ALWKTMLKKLGTMALHAGKAAFGAAADTISQ
  • Function:Antibacterial activity against Gram-positive bacteria S.aureus and E.faecalis, and Gram-negative bacteria P.aeruginosa and E.coli.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000453    From 1 To 31 E-value: 0.000000000007 Score: 60.8
        ALWKTMLKKLGTMALHAGKAAFGAAADTISQ
  • 2. L11A012112    From 1 To 31 E-value: 0.0000000002 Score: 56.2
        ALWKTMLKKLGTVALHAGKAALGAVADTISQ
  • 3. L12A06611|    From 45 To 75 E-value: 0.000000003 Score: 52
        AMWKDVLKKIGTVALHAGKAALGAVADTISQ
  • 4. L02A000956    From 1 To 31 E-value: 0.000000004 Score: 52
        ALWKDVLKKIGTVALHAGKAALGAVADTISQ
  • 5. L12A06182|    From 45 To 75 E-value: 0.000000004 Score: 51.6
        AMWKDVLKKIGTVALHAGKAALGAVADTISQ

Structure

  •   Domains
  •   1  Name:Dermaseptin    Interpro Link:IPR022731
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  E. coli  MIC:  31.0672 μg/ml  (9.7 μM)  
  •   2  Target:  S. aureus  MIC:  121.706 μg/ml  (38 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Ferrara L.,Scaloni A.,Sebben A.,da Silva L.R.,Batista C.V.F.,
  •   Title:Antimicrobial peptides from the Brazilian frog Phyllomedusa distincta.
  •   Journal:Peptides, 1999, 20, 679-686  [MEDLINE:99404773]

Comments

  •   Comments

  •     No comments found on LAMP database



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