Record in detail


General Info

  • lamp_id:L01A000455
  • Name:DDQ2_PHYDS
  • FullName:Dermadistinctin-Q2
  • Source:Phyllomedusa distincta
  • Mass:2669.2 Da
  • Sequence Length:25 aa
  • Isoelectric Point:9.45
  • Activity:Antibacterial
  • Sequence
        GLWSKIKEAAKTAGLMAMGFVNDMV
  • Function:Antibacterial activity against Gram-positive bacteria S.aureus and E.faecalis, and Gram-negative bacteria P.aeruginosa and E.coli.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000455    From 1 To 25 E-value: 0.000000004 Score: 52
        GLWSKIKEAAKTAGLMAMGFVNDMV
  • 2. L01A002484    From 24 To 48 E-value: 0.00000001 Score: 50.1
        GLWSKIKEAAKTAGKMAMGFVNDMV
  • 3. L02A000940    From 1 To 25 E-value: 0.00000002 Score: 49.3
        GLWSKIKEAAKTAGKMAMGFVNDMV
  • 4. L13A025397    From 1 To 25 E-value: 0.0000003 Score: 45.4
        GLWSKIKEAAKTAGKAAMGFVNEMV
  • 5. L13A011220    From 1 To 25 E-value: 0.0000003 Score: 45.4
        GLWSKIKEAAKTAGKAAMGFVNEMV

Structure

  •   Domains
  •   1  Name:Dermaseptin    Interpro Link:IPR022731
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  E. coli  MIC:  14.9475 μg/ml  (5.6 μM)  
  •   2  Target:  S. aureus  MIC:  58.7224 μg/ml  (22 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Ferrara L.,Scaloni A.,Sebben A.,da Silva L.R.,Batista C.V.F.,
  •   Title:Antimicrobial peptides from the Brazilian frog Phyllomedusa distincta.
  •   Journal:Peptides, 1999, 20, 679-686  [MEDLINE:99404773]

Comments

  •   Comments

  •     No comments found on LAMP database



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