Record in detail
General Info
- lamp_id:L01A000456
- Name:RN1T_RANTE
- FullName:Ranatuerin-1T
- Source:Rana temporaria
- Mass:3400.1 Da
- Sequence Length:33 aa
- Isoelectric Point:10.14
- Activity:Antibacterial
- Sequence
GLLSGLKKVGKHVAKNVAVSLMDSLKCKISGDC - Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. No activity against C.albicans.
Cross-Linking
- Cross-linking
- 1 Database:APD 113
- 2 Database:CAMP CAMPSQ423
- 3 Database:DBAASP 8579
- 4 Database:dbAMP dbAMP_03624
- 5 Database:DRAMP DRAMP02243
- 6 Database:SATPdb satpdb20193
- 7 Database:Uniprot P82740
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000456 From 1 To 33 E-value: 0.0000000000008 Score: 63.9
GLLSGLKKVGKHVAKNVAVSLMDSLKCKISGDC - 2. L02A001928 From 1 To 33 E-value: 0.00000002 Score: 49.7
GLFSAFKKVGKNVLKNVAGSLMDNLKCKVSGEC - 3. L01A000706 From 1 To 33 E-value: 0.0000001 Score: 47.4
GLFNVFKKVGKNVLKNVAGSLMDNLKCKVSGEC - 4. L12A07361| From 51 To 78 E-value: 0.000002 Score: 42.7
LKTAGKNVAKNVAGSLLDQLKCKISGGC - 5. L12A07178| From 51 To 78 E-value: 0.000002 Score: 42.7
LKTAGKNVAKNVAGSLLDQLKCKISGGC
Structure
- Domains
- 1 Name:Antimicrobial_frog_2 Interpro Link:IPR012521
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: E. coli MIC: 136.004 μg/ml (40 μM)
- 2 Target: S. aureus MIC: 408.012 μg/ml (120 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Barra D.,Mignogna G.,Simmaco M.,
- Title:Antimicrobial peptides from amphibian skin: what do they tell us?
- Journal:Biopolymers, 1998, 47, 435-450 [MEDLINE:99266278]
- [2] Conlon J.M.,Knoop F.C.,Goraya J.,
- Title:Ranatuerin 1T: an antimicrobial peptide isolated from the skin of the frog, Rana temporaria.
- Journal:Peptides, 1999, 20, 159-163 [MEDLINE:99349732]
Comments
- Comments
No comments found on LAMP database