Record in detail


General Info

  • lamp_id:L01A000457
  • Name:RAN1_LITCT
  • FullName:Ranatuerin-1
  • Source:Lithobates catesbeiana
  • Mass:2651.3 Da
  • Sequence Length:25 aa
  • Isoelectric Point:10.35
  • Activity:Antibacterial, Antifungal
  • Sequence
        SMLSVLKNLGKVGLGFVACKINKQC
  • Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. Has activity against C.albicans.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A07324|    From 42 To 66 E-value: 0.000000005 Score: 51.6
        SMLSVLKNLGKVGLGFVACKINKQC
  • 2. L12A07141|    From 42 To 66 E-value: 0.000000005 Score: 51.6
        SMLSVLKNLGKVGLGFVACKINKQC
  • 3. L01A000457    From 1 To 25 E-value: 0.00000001 Score: 50.4
        SMLSVLKNLGKVGLGFVACKINKQC
  • 4. L12A07322|    From 42 To 66 E-value: 0.00000002 Score: 50.1
        SMFSVLKNLGKVGLGFVACKVNKQC
  • 5. L11A002391    From 1 To 25 E-value: 0.00000002 Score: 49.7
        SMLSVLKNLGRVGLGFVACKINKQC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_2    Interpro Link:IPR012521
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  S.aureus  MIC:  132.57 μg/ml  (50.0019 μM)  
  •   2  Target:  E.coli  MIC:  5.3 μg/ml  (1.99902 μM)  
  •   3  Target:  C.albicans  MIC:  185.59 μg/ml  (69.9996 μM)  
  •   4  Target:  E. coli  MIC:  34.4669 μg/ml  (13 μM)  
  •   5  Target:  S. aureus  MIC:  66.2825 μg/ml  (25 μM)  

Toxicity

  •   Toxicity

Reference

  •   Reference
  •   [1]  Conlon J.M.,Knoop F.C.,Goraya J.,
  •   Title:Ranatuerins: antimicrobial peptides isolated from the skin of the American bullfrog, Rana catesbeiana.
  •   Journal:Biochem. Biophys. Res. Commun., 1998, 250, 589-592  [PubMed:9784389]

Comments

  •   Comments

    •     No comments found on LAMP database



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