Record in detail

General Info

lamp_id:L01A000460
Name:RAN4_LITCT
FullName:Ranatuerin-4
Source:Lithobates catesbeiana
Mass:2653.3 Da
Sequence Length:24 aa
Isoelectric Point:10.51
Activity:Antibacterial
Sequence
FLPFIARLAAKVFPSIICSVTKKC
Function:Antibacterial activity against Gram-positive bacterium S.aureus.

Cross-Linking

Cross-linking
1 Database:APD 117
2 Database:CAMP CAMPSQ427
3 Database:DBAASP 1013
4 Database:dbAMP dbAMP_01999
5 Database:DRAMP DRAMP02231
6 Database:SATPdb satpdb10560
7 Database:Uniprot P82819
8 Database:AMD RT4_RANCA

Top similar AMPs

Top similar AMPs on LAMP
1. L12A07358| From 47 To 70 E-value: 0.00000001 Score: 50.4
FLPFIARLAAKVFPSIICSVTKKC
2. L01A000460 From 1 To 24 E-value: 0.00000004 Score: 48.5
FLPFIARLAAKVFPSIICSVTKKC
3. L01A000447 From 1 To 24 E-value: 0.00001 Score: 40.4
FLPVVAGLAAKVLPSIICAVTKKC
4. L01A000636 From 1 To 24 E-value: 0.00004 Score: 38.5
FLPAIFRMAAKVVPTIICSITKKC
5. L12A09653| From 21 To 44 E-value: 0.0001 Score: 37
FLPIIAGVAAKVFPKIFCAISKKC

Structure

Domains
1 Name:Antimicrobial_frog_1 Interpro Link:IPR012520

Structures

Activity

Antibacterial Activities
1 Target: S.aureus MIC: 145.93 μg/ml (54.9994 μM)
2 Target: S. aureus MIC: 145.932 μg/ml (55 μM)

Toxicity

Toxicity

Reference

Reference
[1] Conlon J.M.,Knoop F.C.,Goraya J.,
Title:Ranatuerins: antimicrobial peptides isolated from the skin of the American bullfrog, Rana catesbeiana.
Journal:Biochem. Biophys. Res. Commun., 1998, 250, 589-592 [PubMed:9784389]

Comments

Comments