Record in detail
General Info
- lamp_id:L01A000466
- Name:RN2LA_RANLU
- FullName:Ranatuerin-2La
- Source:Rana luteiventris
- Mass:3291 Da
- Sequence Length:32 aa
- Isoelectric Point:10.06
- Activity:Antibacterial, Antifungal
- Sequence
GILDSFKGVAKGVAKDLAGKLLDKLKCKITGC - Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. Weak activity against C.albicans.
Cross-Linking
- Cross-linking
- 1 Database:APD 118
- 2 Database:CAMP CAMPSQ433
- 3 Database:DBAASP 1804
- 4 Database:dbAMP dbAMP_03038
- 5 Database:DRAMP DRAMP02254
- 6 Database:SATPdb satpdb21808
- 7 Database:Uniprot P82828
- 8 Database:AMD RT2LA_RANLU
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000466 From 1 To 32 E-value: 0.000000000008 Score: 60.8
GILDSFKGVAKGVAKDLAGKLLDKLKCKITGC - 2. L02A001435 From 1 To 32 E-value: 0.0000000001 Score: 57
GILSSFKGVAKGVAKNLAGKLLDELKCKITGC - 3. L02A001410 From 1 To 32 E-value: 0.0000000001 Score: 57
GLLSSFKGVAKGVAKDLAGKLLEKLKCKITGC - 4. L01A003106 From 1 To 32 E-value: 0.0000000002 Score: 56.6
GILSSFKGVAKGVAKDLAGKLLETLKCKITGC - 5. L01A000539 From 1 To 32 E-value: 0.0000000007 Score: 54.3
GILSTFKGLAKGVAKDLAGNLLDKFKCKITGC
Structure
- Domains
- 1 Name:Antimicrobial_frog_2 Interpro Link:IPR012521
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: E. coli MIC: 13.164 μg/ml (4 μM)
- 2 Target: S. aureus MIC: 36.201 μg/ml (11 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
- Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
- Journal:Eur. J. Biochem., 2000, 267, 894-900 [MEDLINE:20117700]
Comments
- Comments
No comments found on LAMP database