Record in detail


General Info

  • lamp_id:L01A000466
  • Name:RN2LA_RANLU
  • FullName:Ranatuerin-2La
  • Source:Rana luteiventris
  • Mass:3291 Da
  • Sequence Length:32 aa
  • Isoelectric Point:10.06
  • Activity:Antibacterial, Antifungal
  • Sequence
        GILDSFKGVAKGVAKDLAGKLLDKLKCKITGC
  • Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. Weak activity against C.albicans.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000466    From 1 To 32 E-value: 0.000000000008 Score: 60.8
        GILDSFKGVAKGVAKDLAGKLLDKLKCKITGC
  • 2. L02A001435    From 1 To 32 E-value: 0.0000000001 Score: 57
        GILSSFKGVAKGVAKNLAGKLLDELKCKITGC
  • 3. L02A001410    From 1 To 32 E-value: 0.0000000001 Score: 57
        GLLSSFKGVAKGVAKDLAGKLLEKLKCKITGC
  • 4. L01A003106    From 1 To 32 E-value: 0.0000000002 Score: 56.6
        GILSSFKGVAKGVAKDLAGKLLETLKCKITGC
  • 5. L01A000539    From 1 To 32 E-value: 0.0000000007 Score: 54.3
        GILSTFKGLAKGVAKDLAGNLLDKFKCKITGC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_2    Interpro Link:IPR012521
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  E. coli  MIC:  13.164 μg/ml  (4 μM)  
  •   2  Target:  S. aureus  MIC:  36.201 μg/ml  (11 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
  •   Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
  •   Journal:Eur. J. Biochem., 2000, 267, 894-900  [MEDLINE:20117700]

Comments

  •   Comments

  •     No comments found on LAMP database



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