Record in detail
General Info
- lamp_id:L01A000467
- Name:RN2LB_RANLU
- FullName:Ranatuerin-2Lb
- Source:Rana luteiventris
- Mass:3200.9 Da
- Sequence Length:32 aa
- Isoelectric Point:10.23
- Activity:Antibacterial, Antifungal
- Sequence
GILSSIKGVAKGVAKNVAAQLLDTLKCKITGC - Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. Has activity against C.albicans.
Cross-Linking
- Cross-linking
- 1 Database:APD 119
- 2 Database:CAMP CAMPSQ434
- 3 Database:DBAASP 1805
- 4 Database:dbAMP dbAMP_03091
- 5 Database:DRAMP DRAMP02255
- 6 Database:SATPdb satpdb16563
- 7 Database:Uniprot P82829
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000467 From 1 To 32 E-value: 0.000000000003 Score: 62
GILSSIKGVAKGVAKNVAAQLLDTLKCKITGC - 2. L03A000038 From 1 To 32 E-value: 0.000000000007 Score: 60.8
GILSSFKGVAKGVAKNVAAQLLDTLKCKITGC - 3. L11A004383 From 1 To 32 E-value: 0.0000000002 Score: 56.2
GILSSFKDVAKGVAKNVAAQLLDKLKCKITGC - 4. L02A001435 From 1 To 32 E-value: 0.0000000008 Score: 54.3
GILSSFKGVAKGVAKNLAGKLLDELKCKITGC - 5. L01A003106 From 1 To 32 E-value: 0.000000002 Score: 52.8
GILSSFKGVAKGVAKDLAGKLLETLKCKITGC
Structure
- Domains
- 1 Name:Antimicrobial_frog_2 Interpro Link:IPR012521
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: E. coli MIC: 12.8036 μg/ml (4 μM)
- 2 Target: S. aureus MIC: 12.8036 μg/ml (4 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
- Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
- Journal:Eur. J. Biochem., 2000, 267, 894-900 [MEDLINE:20117700]
Comments
- Comments
No comments found on LAMP database