Record in detail
General Info
- lamp_id:L01A000468
- Name:RN2B_LITBE
- FullName:Ranatuerin-2B
- Source:Lithobates berlandieri
- Mass:2864.5 Da
- Sequence Length:28 aa
- Isoelectric Point:9.55
- Activity:Antibacterial, Antifungal
- Sequence
GLLDTIKGVAKTVAASMLDKLKCKISGC - Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. Has activity against C.albicans.
Cross-Linking
- Cross-linking
- 1 Database:APD 120
- 2 Database:CAMP CAMPSQ435
- 3 Database:DBAASP 1816
- 4 Database:dbAMP dbAMP_03525
- 5 Database:DRAMP DRAMP02256
- 6 Database:SATPdb satpdb26803
- 7 Database:Uniprot P82840
- 8 Database:AMD RT2B_RANBE
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000468 From 1 To 28 E-value: 0.0000000005 Score: 55.1
GLLDTIKGVAKTVAASMLDKLKCKISGC - 2. L02A001418 From 1 To 28 E-value: 0.000000007 Score: 51.2
GLMDTIKGVAKTVAASWLDKLKCKITGC - 3. L01A003327 From 1 To 28 E-value: 0.00000001 Score: 50.1
GIMDTVKGVAKTVAASLLDKLKCKITGC - 4. L102656000 From 1 To 28 E-value: 0.00000005 Score: 48.1
GLMDTIKGVAKNVAASLLEKLKCKVTGC - 5. L12A07248| From 44 To 71 E-value: 0.0000003 Score: 45.8
GLMDTVKNVAKNLAGHMLDKLKCKITGC
Structure
- Domains
- 1 Name:Antimicrobial_frog_2 Interpro Link:IPR012521
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: E. coli MIC: 5.729 μg/ml (2 μM)
- 2 Target: S. aureus MIC: 5.729 μg/ml (2 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
- Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
- Journal:Eur. J. Biochem., 2000, 267, 894-900 [MEDLINE:20117700]
Comments
- Comments
No comments found on LAMP database