Record in detail


General Info

  • lamp_id:L01A000473
  • Name:RN2CB_RANCL
  • FullName:Ranatuerin-2Cb
  • Source:Rana clamitans
  • Mass:2786.4 Da
  • Sequence Length:27 aa
  • Isoelectric Point:10.23
  • Activity:Antibacterial, Antifungal
  • Sequence
        GLFLDTLKGLAGKLLQGLKCIKAGCKP
  • Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. Has activity against C.albicans.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000473    From 1 To 27 E-value: 0.000000003 Score: 52.4
        GLFLDTLKGLAGKLLQGLKCIKAGCKP
  • 2. L12A07138|    From 44 To 70 E-value: 0.0000006 Score: 44.7
        GVFLDTLKGLAGKMLESLKCKIAGCKP
  • 3. L12A07139|    From 44 To 70 E-value: 0.0000006 Score: 44.7
        GVFLDTLKGLAGKMLESLKCKIAGCKP
  • 4. L13A027960    From 1 To 27 E-value: 0.000001 Score: 43.5
        GVFLDTLKGLAGKMLESLKCKIAGCKP
  • 5. L12A07043|    From 44 To 70 E-value: 0.00001 Score: 40.4
        GIFLDTLKNMAGKMLESLKCKLFGCKP

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  S.aureus  MIC:  111.46 μg/ml  (40.0014 μM)  
  •   2  Target:  E.coli  MIC:  5.57 μg/ml  (1.999 μM)  
  •   3  Target:  C.albicans  MIC:  128.17 μg/ml  (45.9984 μM)  
  •   4  Target:  E. coli  MIC:  5.5728 μg/ml  (2 μM)  
  •   5  Target:  S. aureus  MIC:  111.456 μg/ml  (40 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Conlon J.M.,Knoop F.C.,Basir Y.J.,Halverson T.,
  •   Title:Purification and characterization of antimicrobial peptides from the skin of the North American green frog Rana clamitans.
  •   Journal:Peptides, 2000, 21, 469-476  [MEDLINE:20283865]

Comments

  •   Comments

    •     No comments found on LAMP database



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