Record in detail


General Info

  • lamp_id:L01A000487
  • Name:BR2_RANBP
  • FullName:Brevinin-2
  • Source:Rana brevipoda porsa
  • Mass:3253.8 Da
  • Sequence Length:33 aa
  • Isoelectric Point:9.6
  • Activity:Antibacterial
  • Sequence
        GLLDSLKGFAATAGKGVLQSLLSTASCKLAKTC
  • Function:Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species, and a very high hemolytic activity.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000487    From 1 To 33 E-value: 0.000000000002 Score: 62.4
        GLLDSLKGFAATAGKGVLQSLLSTASCKLAKTC
  • 2. L12A07158|    From 42 To 74 E-value: 0.000000002 Score: 52.8
        GLMDSLKGLAATAGKTVLQGLLKTASCKLEKTC
  • 3. L02A001396    From 1 To 33 E-value: 0.000000004 Score: 52
        GLMDSLKGLAATAGKTVLQGLLKTASCKLEKTC
  • 4. L01A003830    From 42 To 74 E-value: 0.000000006 Score: 51.2
        GILDTLKEFGKTAAKGIAQSLLSTASCKLAKTC
  • 5. L10D1MIZ80    From 1 To 33 E-value: 0.00000001 Score: 50.4
        GILDTLKEFGKTAAKGIAQSLLSTASCKLAKTC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_2    Interpro Link:IPR012521
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  S.aureus  MIC:  8 μg/ml  (2.45866 μM)  
  •   2  Target:  E.coli  MIC:  4 μg/ml  (1.22933 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Nakajima T.,Hagiwara K.,Morikawa N.,
  •   Title:Brevinin-1 and -2, unique antimicrobial peptides from the skin of the frog, Rana brevipoda porsa.
  •   Journal:Biochem. Biophys. Res. Commun., 1992, 189, 184-190  [MEDLINE:93080555]

Comments

  •   Comments

    •     No comments found on LAMP database



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