Record in detail


General Info

  • lamp_id:L01A000488
  • Name:BR2E_RANES
  • FullName:Brevinin-2E
  • Source:Rana esculenta
  • Mass:3364 Da
  • Sequence Length:33 aa
  • Isoelectric Point:10.23
  • Activity:Antibacterial
  • Sequence
        GIMDTLKNLAKTAGKGALQSLLNKASCKLSGQC
  • Function:Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species, and hemolytic activity.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000488    From 1 To 33 E-value: 0.0000000000005 Score: 64.7
        GIMDTLKNLAKTAGKGALQSLLNKASCKLSGQC
  • 2. L01A003319    From 1 To 33 E-value: 0.000000000001 Score: 63.2
        GIMDTLKNLAKTAGKGALQSLLNHASCKLSGQC
  • 3. L03A000120    From 42 To 74 E-value: 0.000000000005 Score: 61.6
        GILDTLKHLAKTAGKGALQSLLNHASCKLSGQC
  • 4. L03A000040    From 1 To 33 E-value: 0.00000000001 Score: 60.5
        GIMDTLKNLAKTAGKGALQSLLNHASCKLSKQC
  • 5. L01A002922    From 1 To 33 E-value: 0.00000000001 Score: 60.5
        GILDTLKHLAKTAGKGALQSLLNHASCKLSGQC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_2    Interpro Link:IPR012521
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  E. coli D21  MIC:  1.68 μg/ml  (0.499405 μM)  
  •   2  Target:  B. megaterium BmII  MIC:  0.67 μg/ml  (0.199168 μM)  
  •   3  Target:  S. aureus Cowan 1  MIC:  6.73 μg/ml  (2.00059 μM)  
  •   4  Target:  P.aeruginosa ATCC15692  MIC:  100.92 μg/ml  (30 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Bossa F.,Barra D.,Mignogna G.,Simmaco M.,
  •   Title:Novel antimicrobial peptides from skin secretion of the European frog Rana esculenta.
  •   Journal:FEBS Lett., 1993, 324, 159-161  [MEDLINE:93285327]

Comments

  •   Comments

    •     No comments found on LAMP database



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