Record in detail


General Info

  • lamp_id:L01A000495
  • Name:LAFA_LACJO
  • FullName:Bacteriocin lactacin-F subunit LafA
  • Source:Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
  • Mass:5615.5 Da
  • Sequence Length:57 aa
  • Isoelectric Point:10.26
  • Activity:Antibacterial
  • Sequence
        RNNWQTNVGGAVGSAMIGATVGGTICGPACAVAGAHYLPILWTAVTAATGGFGKIRK
  • Function:Heat stable bacteriocin active against Enterococcus faecalis and other Lactobacilli.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A08192|    From 19 To 75 E-value: 7e-28 Score: 114
        RNNWQTNVGGAVGSAMIGATVGGTICGPACAVAGAHYLPILWTAVTAATGGFGKIRK
  • 2. L01A000495    From 1 To 57 E-value: 2e-27 Score: 112
        RNNWQTNVGGAVGSAMIGATVGGTICGPACAVAGAHYLPILWTAVTAATGGFGKIRK
  • 3. L13A017148    From 1 To 50 E-value: 4e-23 Score: 98.2
        RNNWQTNVGGAVGSAMIGATVGGTICGPACAVAGAHYLPILWTAVTAATG
  • 4. L12A08154|    From 19 To 75 E-value: 0.0000000000001 Score: 66.6
        RNNWAANIGGVGGATVAGWALGNAVCGPACGFVGAHYVPIAWAGVTAATGGFGKIRK
  • 5. L04ABAC117    From 1 To 57 E-value: 0.0000000000002 Score: 66.2
        RNNWAANIGGVGGATVAGWALGNAVCGPACGFVGAHYVPIAWAGVTAATGGFGKIRK

Structure

  •   Domains
  •   1  Name:Bacteriocin_IIb_lactacin-rel    Interpro Link:IPR019493
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Klaenhammer T.R.,Muriana P.M.,
  •   Title:Cloning, phenotypic expression, and DNA sequence of the gene for lactacin F, an antimicrobial peptide produced by Lactobacillus spp.
  •   Journal:J. Bacteriol., 1991, 173, 1779-1788  [MEDLINE:91154135]
  •   [2]  Klaenhammer T.R.,Muriana P.M.,
  •   Title:Purification and partial characterization of lactacin F, a bacteriocin produced by Lactobacillus acidophilus 11088.
  •   Journal:Appl. Environ. Microbiol., 1991, 57, 114-121  [MEDLINE:91241762]
  •   [3]  Klaenhammer T.R.,Ahn C.,Fremaux C.,
  •   Title:Molecular analysis of the lactacin F operon.
  •   Journal:Appl. Environ. Microbiol., 1993, 59, 3906-3915  [MEDLINE:94113718]
  •   [4]  Barretto C.,Vilanova D.,Desiere F.,Berger B.,Pridmore R.D.,
  •   Title:The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533.
  •   Journal:Proc. Natl. Acad. Sci. U.S.A., 2004, 101, 2512-2517  [PubMed:14983040]

Comments

  •   Comments

  •     No comments found on LAMP database



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