Record in detail
General Info
- lamp_id:L01A000495
- Name:LAFA_LACJO
- FullName:Bacteriocin lactacin-F subunit LafA
- Source:Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
- Mass:5615.5 Da
- Sequence Length:57 aa
- Isoelectric Point:10.26
- Activity:Antibacterial
- Sequence
RNNWQTNVGGAVGSAMIGATVGGTICGPACAVAGAHYLPILWTAVTAATGGFGKIRK - Function:Heat stable bacteriocin active against Enterococcus faecalis and other Lactobacilli.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ462
- 2 Database:dbAMP dbAMP_10602
- 3 Database:DRAMP DRAMP00140
- 4 Database:Uniprot P24022
- 5 Database:BAC BAC105
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L12A08192| From 19 To 75 E-value: 7e-28 Score: 114
RNNWQTNVGGAVGSAMIGATVGGTICGPACAVAGAHYLPILWTAVTAATGGFGKIRK - 2. L01A000495 From 1 To 57 E-value: 2e-27 Score: 112
RNNWQTNVGGAVGSAMIGATVGGTICGPACAVAGAHYLPILWTAVTAATGGFGKIRK - 3. L13A017148 From 1 To 50 E-value: 4e-23 Score: 98.2
RNNWQTNVGGAVGSAMIGATVGGTICGPACAVAGAHYLPILWTAVTAATG - 4. L12A08154| From 19 To 75 E-value: 0.0000000000001 Score: 66.6
RNNWAANIGGVGGATVAGWALGNAVCGPACGFVGAHYVPIAWAGVTAATGGFGKIRK - 5. L04ABAC117 From 1 To 57 E-value: 0.0000000000002 Score: 66.2
RNNWAANIGGVGGATVAGWALGNAVCGPACGFVGAHYVPIAWAGVTAATGGFGKIRK
Structure
- Domains
- 1 Name:Bacteriocin_IIb_lactacin-rel Interpro Link:IPR019493
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Klaenhammer T.R.,Muriana P.M.,
- Title:Cloning, phenotypic expression, and DNA sequence of the gene for lactacin F, an antimicrobial peptide produced by Lactobacillus spp.
- Journal:J. Bacteriol., 1991, 173, 1779-1788 [MEDLINE:91154135]
- [2] Klaenhammer T.R.,Muriana P.M.,
- Title:Purification and partial characterization of lactacin F, a bacteriocin produced by Lactobacillus acidophilus 11088.
- Journal:Appl. Environ. Microbiol., 1991, 57, 114-121 [MEDLINE:91241762]
- [3] Klaenhammer T.R.,Ahn C.,Fremaux C.,
- Title:Molecular analysis of the lactacin F operon.
- Journal:Appl. Environ. Microbiol., 1993, 59, 3906-3915 [MEDLINE:94113718]
- [4] Barretto C.,Vilanova D.,Desiere F.,Berger B.,Pridmore R.D.,
- Title:The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533.
- Journal:Proc. Natl. Acad. Sci. U.S.A., 2004, 101, 2512-2517 [PubMed:14983040]
Comments
- Comments
No comments found on LAMP database