Record in detail
General Info
- lamp_id:L01A000509
- Name:AMYL_LACAM
- FullName:Bacteriocin amylovorin-L
- Source:Lactobacillus amylovorus
- Mass:4881.7 Da
- Sequence Length:50 aa
- Isoelectric Point:10.37
- Activity:Antibacterial
- Sequence
NRWTNAYSAALGCAVPGVKYGKKLGGVWGAVIGGVGGAAVCGLAGYVRKG - Function:This heat stable bacteriocin inhibits the growth of closely related Lactobacillus species. It may act as a pore-forming protein, creating a channel in the cell membrane. It kills Lactobacillus helveticus ATCC 15009, but displays no activity towards Listeria species.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ475
- 2 Database:dbAMP dbAMP_09810
- 3 Database:DRAMP DRAMP00144
- 4 Database:SATPdb satpdb25449
- 5 Database:Uniprot P80696
- 6 Database:BAC BAC095
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L12A08193| From 16 To 65 E-value: 3e-22 Score: 95.5
NRWTNAYSAALGCAVPGVKYGKKLGGVWGAVIGGVGGAAVCGLAGYVRKG - 2. L01A000509 From 1 To 50 E-value: 8e-22 Score: 94
NRWTNAYSAALGCAVPGVKYGKKLGGVWGAVIGGVGGAAVCGLAGYVRKG - 3. L12A08084| From 15 To 62 E-value: 0.015 Score: 30
NRWGDTVLSAASGAGTGIKACKSFG-PWGMAICGVGGAAIGGYFGYTHN - 4. L02A001169 From 1 To 48 E-value: 0.016 Score: 30
NRWGDTVLSAASGAGTGIKACKSFG-PWGMAICGVGGAAIGGYFGYTHN - 5. L12A08876| From 27 To 64 E-value: 0.03 Score: 28.9
AALGCAAGGVKYGRLL-GLWGAAIGGIGGAVVCGYLAYT
Structure
- Domains
- 1 Name:Bacteriocin_IIb_lactacin-rel Interpro Link:IPR019493
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Raymaeckers J.,Busanyova K.,Devreese B.,De Vuyst L.,Contreras B.G.L.,
- Title:Isolation, purification, and amino acid sequence of lactobin A, one of the two bacteriocins produced by Lactobacillus amylovorus LMG P-13139.
- Journal:Appl. Environ. Microbiol., 1997, 63, 13-20 [MEDLINE:97133940]
- [2] Nes I.,Van Beeumen J.,Devreese B.,Holo H.,Callewaert R.,
- Title:Characterization and production of amylovorin L471, a bacteriocin purified from Lactobacillus amylovorus DCE 471 by a novel three-step method.
- Journal:Microbiology, 1999, 145, 2559-2568 [PubMed:10517609]
- [3] Vancanneyt M.,Hoste B.,Neysens P.,Avonts L.,De Vuyst L.,
- Title:The lactobin A and amylovorin L471 encoding genes are identical, and their distribution seems to be restricted to the species Lactobacillus amylovorus that is of interest for cereal fermentations.
- Journal:Int. J. Food Microbiol., 2004, 90, 93-106 [PubMed:14672834]
Comments
- Comments
No comments found on LAMP database