Record in detail


General Info

  • lamp_id:L01A000509
  • Name:AMYL_LACAM
  • FullName:Bacteriocin amylovorin-L
  • Source:Lactobacillus amylovorus
  • Mass:4881.7 Da
  • Sequence Length:50 aa
  • Isoelectric Point:10.37
  • Activity:Antibacterial
  • Sequence
        NRWTNAYSAALGCAVPGVKYGKKLGGVWGAVIGGVGGAAVCGLAGYVRKG
  • Function:This heat stable bacteriocin inhibits the growth of closely related Lactobacillus species. It may act as a pore-forming protein, creating a channel in the cell membrane. It kills Lactobacillus helveticus ATCC 15009, but displays no activity towards Listeria species.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A08193|    From 16 To 65 E-value: 3e-22 Score: 95.5
        NRWTNAYSAALGCAVPGVKYGKKLGGVWGAVIGGVGGAAVCGLAGYVRKG
  • 2. L01A000509    From 1 To 50 E-value: 8e-22 Score: 94
        NRWTNAYSAALGCAVPGVKYGKKLGGVWGAVIGGVGGAAVCGLAGYVRKG
  • 3. L12A08084|    From 15 To 62 E-value: 0.015 Score: 30
        NRWGDTVLSAASGAGTGIKACKSFG-PWGMAICGVGGAAIGGYFGYTHN
  • 4. L02A001169    From 1 To 48 E-value: 0.016 Score: 30
        NRWGDTVLSAASGAGTGIKACKSFG-PWGMAICGVGGAAIGGYFGYTHN
  • 5. L12A08876|    From 27 To 64 E-value: 0.03 Score: 28.9
        AALGCAAGGVKYGRLL-GLWGAAIGGIGGAVVCGYLAYT

Structure

  •   Domains
  •   1  Name:Bacteriocin_IIb_lactacin-rel    Interpro Link:IPR019493
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Raymaeckers J.,Busanyova K.,Devreese B.,De Vuyst L.,Contreras B.G.L.,
  •   Title:Isolation, purification, and amino acid sequence of lactobin A, one of the two bacteriocins produced by Lactobacillus amylovorus LMG P-13139.
  •   Journal:Appl. Environ. Microbiol., 1997, 63, 13-20  [MEDLINE:97133940]
  •   [2]  Nes I.,Van Beeumen J.,Devreese B.,Holo H.,Callewaert R.,
  •   Title:Characterization and production of amylovorin L471, a bacteriocin purified from Lactobacillus amylovorus DCE 471 by a novel three-step method.
  •   Journal:Microbiology, 1999, 145, 2559-2568  [PubMed:10517609]
  •   [3]  Vancanneyt M.,Hoste B.,Neysens P.,Avonts L.,De Vuyst L.,
  •   Title:The lactobin A and amylovorin L471 encoding genes are identical, and their distribution seems to be restricted to the species Lactobacillus amylovorus that is of interest for cereal fermentations.
  •   Journal:Int. J. Food Microbiol., 2004, 90, 93-106  [PubMed:14672834]

Comments

  •   Comments

  •     No comments found on LAMP database



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