Record in detail
General Info
- lamp_id:L01A000513
- Name:CHY1_PAGMA
- FullName:Chrysophsin-1
- Source:Pagrus major
- Mass:2892.4 Da
- Sequence Length:25 aa
- Isoelectric Point:12.81
- Activity:Antibacterial,Anticancer
- Sequence
FFGWLIKGAIHAGKAIHGLIHRRRH - Function:Has antibacterial activity against Gram-positive bacteria B.subtilis ATCC 6633, L.garvieae ATCC 49156 and S.iniae F-8502, and Gram-negative bacteria E.coli WT-2, V.anguillarum ATCC 19264, V.penaeicida KHA, V.harveyi ATCC 14126, V.vulnificus ATCC 33148, A.salmonicida NCMB 1102 and P.putida ATCC 12633. Has hemolytic activity against human red blood cells. Seems to disrupt the membranes by adopting an alpha helical conformation. May play a significant role in innate host defense.
Cross-Linking
- Cross-linking
- 1 Database:APD 339
- 2 Database:CAMP CAMPSQ478
- 3 Database:DBAASP 3173
- 4 Database:dbAMP dbAMP_01658
- 5 Database:DRAMP DRAMP02315
- 6 Database:SATPdb satpdb25643
- 7 Database:Uniprot P83545
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000513 From 1 To 25 E-value: 0.00000001 Score: 50.4
FFGWLIKGAIHAGKAIHGLIHRRRH - 2. L01A000514 From 1 To 25 E-value: 0.00000002 Score: 49.3
FFGWLIRGAIHAGKAIHGLIHRRRH - 3. L11A010487 From 1 To 25 E-value: 0.00000004 Score: 48.5
FFGWLIKGAIHAGKAIHPLIHRRRH - 4. L11A010486 From 1 To 25 E-value: 0.00000004 Score: 48.5
FFGWLIKGAIHAPKAIHGLIHRRRH - 5. L11A010485 From 1 To 25 E-value: 0.00000004 Score: 48.5
FFGWLIKPAIHAGKAIHGLIHRRRH
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Uematsu K.,Morita Y.,Emoto Y.,Tanimoto N.,Iijima N.,
- Title:Purification and characterization of three isoforms of chrysophsin, a novel antimicrobial peptide in the gills of the red sea bream, Chrysophrys major.
- Journal:Eur. J. Biochem., 2003, 270, 675-686 [MEDLINE:22469439]
Comments
- Comments
No comments found on LAMP database