Record in detail
General Info
- lamp_id:L01A000528
- Name:CR16_LITXA
- FullName:Caerin-1.6
- Source:Litoria xanthomera
- Mass:2594.2 Da
- Sequence Length:25 aa
- Isoelectric Point:9.54
- Activity:Antibacterial
- Sequence
GLFSVLGAVAKHVLPHVVPVIAEKL - Function:Antibacterial peptide, that adopts an alpha helical conformation which can disrupt bacterial membranes. Each caerin displays a different antimicrobial specificity.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1140
- 2 Database:DBAASP 1990
- 3 Database:dbAMP dbAMP_03399
- 4 Database:DRAMP DRAMP01556
- 5 Database:SATPdb satpdb18843
- 6 Database:Uniprot P62546
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000528 From 1 To 25 E-value: 0.00000004 Score: 48.5
GLFSVLGAVAKHVLPHVVPVIAEKL - 2. L01A002353 From 1 To 24 E-value: 0.0000001 Score: 47.4
GLFSVLGAVAKHVLPHVVPVIAEK - 3. L01A000103 From 1 To 25 E-value: 0.0000001 Score: 46.6
GLFSVLGSVAKHLLPHVVPVIAEKL - 4. L01A000031 From 1 To 25 E-value: 0.0000003 Score: 45.4
GLLSVLGSVAKHVLPHVVPVIAEKL - 5. L01A000414 From 1 To 25 E-value: 0.0000003 Score: 45.4
GLFGVLGSIAKHVLPHVVPVIAEKL
Activity
- Antibacterial Activities
- 1 Target: E. coli MIC: 49.9902 μg/ml (19.27 μM)
- 2 Target: S. aureus MIC: 5.9926 μg/ml (2.31 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Tyler M.J.,Wallace J.C.,Bowie J.H.,Waugh R.J.,Steinborner S.T.,
- Title:New caerin antibacterial peptides from the skin glands of the Australian tree frog Litoria xanthomera.
- Journal:J. Pept. Sci., 1997, 3, 181-185 [MEDLINE:97374000]
- [2] Tyler M.J.,Bowie J.H.,Waugh R.J.,Steinborner S.T.,
- Title:New caerin antibacterial peptides from the skin glands of the Australian tree frog Litoria xanthomera. Part 2. Sequence determination using mass spectrometry and associated techniques.
- Journal:Rapid Commun. Mass Spectrom., 1997, 11, 997-1000 [MEDLINE:97348590]
Comments
- Comments
No comments found on LAMP database