Record in detail


General Info

  • lamp_id:L01A000531
  • Name:MYR3_MYRBA
  • FullName:Pilosulin-3
  • Source:Myrmecia banksi
  • Mass:2515.2 Da
  • Sequence Length:24 aa
  • Isoelectric Point:10.63
  • Activity:Antibacterial
  • Sequence
        IIGLVSKGTCVLVKTVCKKVLKQG
  • Function:Shows moderate activity against E.coli and S.aureus (MIC<25 uM), slight activity against B.subtilis (MIC<50 uM), and no activity against L.garvieae, P.aeruginosa, C.albicans, and S.cerevisiae. Has no hemolytic nor cytolytic activity. Causes an IgE-independent histamine release.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A08090|    From 51 To 74 E-value: 0.00000009 Score: 47.4
        IIGLVSKGTCVLVKTVCKKVLKQG
  • 2. L01A000531    From 1 To 24 E-value: 0.0000005 Score: 45.1
        IIGLVSKGTCVLVKTVCKKVLKQG
  • 3. L13A021072    From 1 To 23 E-value: 0.000002 Score: 43.1
        IIGLVSKGTCVLVKTVCKKVLKQ
  • 4. L12A05774|    From 1 To 23 E-value: 0.000003 Score: 42
        LIGLVSKGTCVLVKTVCKKVLKQ

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Kubo T.,Taylor R.W.,Imai H.T.,Akagi M.,Inagaki H.,
  •   Title:Molecular cloning and biological characterization of novel antimicrobial peptides, pilosulin 3 and pilosulin 4, from a species of the Australian ant genus Myrmecia.
  •   Journal:Arch. Biochem. Biophys., 2004, 428, 170-178  [PubMed:15246874]

Comments

  •   Comments

    •     No comments found on LAMP database



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