Record in detail

General Info

lamp_id:L01A000537
Name:BR1YC_RANBO
FullName:Brevinin-1BYc
Source:Rana boylii
Mass:2528.2 Da
Sequence Length:24 aa
Isoelectric Point:9.67
Activity:Antibacterial, Antifungal
Sequence
FLPILASLAATLGPKLLCLITKKC
Function:Antibacterial activity against Gram-positive bacterium S.aureus. Weak antifungal activity against C.albicans.

Cross-Linking

Cross-linking
1 Database:APD 886
2 Database:CAMP CAMPSQ501
3 Database:DBAASP 3538
4 Database:dbAMP dbAMP_02053
5 Database:DRAMP DRAMP01962
6 Database:SATPdb satpdb19044
7 Database:Uniprot P84113

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000537 From 1 To 24 E-value: 0.0000001 Score: 46.6
FLPILASLAATLGPKLLCLITKKC
2. L01A000536 From 1 To 24 E-value: 0.000002 Score: 43.1
FLPILASLAAKLGPKLFCLVTKKC
3. L01A000535 From 1 To 24 E-value: 0.000003 Score: 42.4
FLPILASLAAKFGPKLFCLVTKKC
4. L01A000435 From 1 To 24 E-value: 0.00005 Score: 38.1
FLPMLAGLAASMVPKLVCLITKKC
5. L11A004418 From 1 To 24 E-value: 0.00008 Score: 37.7
FLPILASLAAKFGPKLFSLVTKKS

Structure

Domains
1 Name:Antimicrobial_frog_1 Interpro Link:IPR012520

Structures

Activity

Antibacterial Activities
1 Target: S. aureus MIC: 20.2256 μg/ml (8 μM)

Toxicity

Toxicity

Reference

Reference
[1] Nielsen P.F.,Davidson C.,Patel M.,Sonnevend A.,Conlon J.M.,
Title:Isolation of peptides of the brevinin-1 family with potent candidacidal activity from the skin secretions of the frog Rana boylii.
Journal:J. Pept. Res., 2003, 62, 207-213 [PubMed:14531844]

Comments

Comments