Record in detail
General Info
- lamp_id:L01A000539
- Name:RN2BA_RANBO
- FullName:Ranatuerin-2BYa
- Source:Rana boylii
- Mass:3311 Da
- Sequence Length:32 aa
- Isoelectric Point:10.14
- Activity:Antibacterial
- Sequence
GILSTFKGLAKGVAKDLAGNLLDKFKCKITGC - Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. Weak hemolytic activity.
Cross-Linking
- Cross-linking
- 1 Database:APD 887
- 2 Database:CAMP CAMPSQ503
- 3 Database:DBAASP 3539
- 4 Database:dbAMP dbAMP_03093
- 5 Database:DRAMP DRAMP02258
- 6 Database:SATPdb satpdb28306
- 7 Database:Uniprot P84114
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000539 From 1 To 32 E-value: 0.000000000002 Score: 62.8
GILSTFKGLAKGVAKDLAGNLLDKFKCKITGC - 2. L12A03092| From 1 To 31 E-value: 0.00000000007 Score: 57.8
GILSTFKGLAKGVAKDLAGKLLDKFKCKITG - 3. L01A000466 From 1 To 32 E-value: 0.0000000007 Score: 54.3
GILDSFKGVAKGVAKDLAGKLLDKLKCKITGC - 4. L02A001410 From 1 To 32 E-value: 0.000000001 Score: 53.9
GLLSSFKGVAKGVAKDLAGKLLEKLKCKITGC - 5. L02A001435 From 1 To 32 E-value: 0.000000001 Score: 53.5
GILSSFKGVAKGVAKNLAGKLLDELKCKITGC
Structure
- Domains
- 1 Name:Antimicrobial_frog_2 Interpro Link:IPR012521
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: E. coli MIC: 23.177 μg/ml (7 μM)
- 2 Target: S. aureus MIC: 89.397 μg/ml (27 μM)
Toxicity
- Toxicity
Reference
- Reference
- [1] Nielsen P.F.,Davidson C.,Patel M.,Sonnevend A.,Conlon J.M.,
- Title:Isolation of peptides of the brevinin-1 family with potent candidacidal activity from the skin secretions of the frog Rana boylii.
- Journal:J. Pept. Res., 2003, 62, 207-213 [PubMed:14531844]
Comments
- Comments
No comments found on LAMP database