Record in detail


General Info

  • lamp_id:L01A000546
  • Name:CECB_DROSI
  • FullName:Cecropin-B
  • Source:Drosophila simulans
  • Mass:4297.9 Da
  • Sequence Length:40 aa
  • Isoelectric Point:12.1
  • Activity:Antibacterial
  • Sequence
        AGWLRKLGKKIERIGQHTRDASIQVLGIAQQAANVAATAR
  • Function:Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000200    From 23 To 62 E-value: 8e-18 Score: 80.9
        AGWLRKLGKKIERIGQHTRDASIQVLGIAQQAANVAATAR
  • 2. L12A08719|    From 23 To 62 E-value: 8e-18 Score: 80.9
        AGWLRKLGKKIERIGQHTRDASIQVLGIAQQAANVAATAR
  • 3. L03A000201    From 23 To 62 E-value: 8e-18 Score: 80.9
        AGWLRKLGKKIERIGQHTRDASIQVLGIAQQAANVAATAR
  • 4. L03A000202    From 23 To 62 E-value: 9e-18 Score: 80.5
        AGWLRKLGKKIERIGQHTRDASIQVLGIAQQAANVAATAR
  • 5. L01A000546    From 1 To 40 E-value: 2e-17 Score: 79
        AGWLRKLGKKIERIGQHTRDASIQVLGIAQQAANVAATAR

Structure

  •   Domains
  •   1  Name:Cecropin    Interpro Link:IPR000875
  •   2  Name:Cecropin_diptera    Interpro Link:IPR020400
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Chigusa S.I.,Takahata N.,Satta Y.,Date A.,
  •   Title:Evolutionary history and mechanism of the Drosophila cecropin gene family.
  •   Journal:Immunogenetics, 1998, 47, 417-429  [MEDLINE:98221115]
  •   [2]  Aguade M.,Ramos-Onsins S.,
  •   Title:Molecular evolution of the Cecropin multigene family in Drosophila: functional genes vs pseudogenes.
  •   Journal:Genetics, 1998, 150, 157-171  [MEDLINE:98393576]
  •   [3]  
  •   Title:Evolution of genes and genomes on the Drosophila phylogeny.
  •   Journal:Nature, 2007, 450, 203-218  [PubMed:17994087]

Comments

  •   Comments

  •     No comments found on LAMP database



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