Record in detail

lamp_id:L01A000555
Name:LANA_STRPY
FullName:Lantibiotic streptococcin A-FF22
Source:Streptococcus pyogenes
Mass:2868.3 Da
Sequence Length:26 aa
Isoelectric Point:8.08
Activity:Antibacterial
Sequence
GKNGVFKTISHECHLNTWAFLATCCS
Function:Lanthionine-containing peptide antibiotic (lantibiotic) active on certain Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.

Top similar AMPs on LAMP
1. L12A06735| From 26 To 51 E-value: 0.00000000003 Score: 59.3
GKNGVFKTISHECHLNTWAFLATCCS
2. L12A06747| From 26 To 51 E-value: 0.00000000003 Score: 58.9
GKNGVFKTISHECHLNTWAFLATCCS
3. L12A09455| From 26 To 51 E-value: 0.00000000004 Score: 58.5
GKNGVFKTISHECHLNTWAFLATCCS
4. L01A000555 From 1 To 26 E-value: 0.0000000001 Score: 56.6
GKNGVFKTISHECHLNTWAFLATCCS
5. L12A07940| From 26 To 49 E-value: 0.0000000005 Score: 55.1
NGVFKTISHECHLNTWAFLATCCS

Reference
[1] Tagg J.R.,Ferretti J.J.,Hynes W.L.,
Title:Cloning of the gene encoding Streptococcin A-FF22, a novel lantibiotic produced by Streptococcus pyogenes, and determination of its nucleotide sequence.
Journal:Appl. Environ. Microbiol., 1993, 59, 1969-1971 [MEDLINE:93319301]
[2] Sahl H.-G.,Stefanovic S.,Metzger J.,Carne A.,Jack R.W.,
Title:Elucidation of the structure of SA-FF22, a lanthionine-containing antibacterial peptide produced by Streptococcus pyogenes strain FF22.
Journal:Eur. J. Biochem., 1994, 220, 455-462 [MEDLINE:94170794]