Record in detail


General Info

  • lamp_id:L01A000556
  • Name:PPA1_PEDAC
  • FullName:Bacteriocin pediocin PA-1
  • Source:Pediococcus acidilactici
  • Mass:4628.2 Da
  • Sequence Length:44 aa
  • Isoelectric Point:8.67
  • Activity:Antibacterial
  • Sequence
        KYYGNGVTCGKHSCSVDWGKATTCIINNGAMAWATGGHQGNHKC
  • Function:Bactericidal activity (effective inhibitor of L.monocytogenes).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A06361|    From 8 To 51 E-value: 2e-21 Score: 93.2
        KYYGNGVTCGKHSCSVDWGKATTCIINNGAMAWATGGHQGNHKC
  • 2. L12A07949|    From 19 To 62 E-value: 2e-21 Score: 92.8
        KYYGNGVTCGKHSCSVDWGKATTCIINNGAMAWATGGHQGNHKC
  • 3. L12A07974|    From 19 To 62 E-value: 2e-21 Score: 92.4
        KYYGNGVTCGKHSCSVDWGKATTCIINNGAMAWATGGHQGNHKC
  • 4. L12A09062|    From 19 To 62 E-value: 4e-21 Score: 91.7
        KYYGNGVTCGKHSCSVDWGKATTCIINNGAMAWATGGHQGDHKC
  • 5. L12A00427|    From 7 To 50 E-value: 7e-21 Score: 90.9
        KYYGNGVTCGKHSCSVDWGKATTCIINNGAMAWATGGHQGNHKC

Structure

  •   Domains
  •   1  Name:Bacteriocin_IIa    Interpro Link:IPR002633
  •   2  Name:Bacteriocin_IIa_CS    Interpro Link:IPR023384
  •   3  Name:Bacteriocin_IIa_dom    Interpro Link:IPR023388
  •   4  Name:Bacteriocin_signal_motif    Interpro Link:IPR010133
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Pucci M.J.,Ledeboer A.M.,Kunka B.S.,Gonzalez C.F.,Marugg J.D.,
  •   Title:Cloning, expression, and nucleotide sequence of genes involved in production of pediocin PA-1, and bacteriocin from Pediococcus acidilactici PAC1.0.
  •   Journal:Appl. Environ. Microbiol., 1992, 58, 2360-2367  [MEDLINE:92384551]
  •   [2]  Nes I.F.,Pelaz C.,Sletten K.,Meyer J.N.,Lozano J.C.N.,
  •   Title:Purification and amino acid sequence of a bacteriocin produced by Pediococcus acidilactici.
  •   Journal:J. Gen. Microbiol., 1992, 138, 1985-1990  [MEDLINE:93019000]
  •   [3]  van Wassenaar P.D.,Chopko A.L.,Henderson J.T.,
  •   Title:Purification and primary structure of pediocin PA-1 produced by Pediococcus acidilactici PAC-1.0.
  •   Journal:Arch. Biochem. Biophys., 1992, 295, 5-12  [MEDLINE:92246549]
  •   [4]  Ray B.R.,Bukhtiyarova M.B.,Motlagh A.M.,
  •   Title:Complete nucleotide sequence of pSMB 74, a plasmid encoding the production of pediocin AcH in Pediococcus acidilactici.
  •   Journal:Lett. Appl. Microbiol., 1994, 18, 305-312  [MEDLINE:94288967]

Comments

  •   Comments

    •     No comments found on LAMP database



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