Record in detail


General Info

  • lamp_id:L01A000557
  • Name:GYMN_GYMCH
  • FullName:Gymnin
  • Source:Gymnocladus chinensis
  • Mass:1171.2 Da
  • Sequence Length:10 aa
  • Isoelectric Point:3.88
  • Activity:Antifungal, Antiviral
  • Sequence
        KTCENLADDY
  • Function:Exerts antifungal activity against F.oxysporum and M.arachidicola, with an IC(50) of 2 uM for the former fungus and 10 uM, respectively. Has weak mitogenic activity against murine splenocytes. Displays antiproliferative activity on a human hepatoma cell line and mouse leukemia cell lines. Inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000557    From 1 To 10 E-value: 0.3 Score: 24.3
        KTCENLADDY
  • 2. L03A000111    From 28 To 37 E-value: 1.1 Score: 22.7
        KTCENLADKY
  • 3. L01A003067    From 28 To 37 E-value: 1.1 Score: 22.3
        KTCENLADKY
  • 4. L11A002570    From 29 To 38 E-value: 1.4 Score: 22.3
        KTCENLADTY
  • 5. L01A000009    From 1 To 10 E-value: 1.4 Score: 22.3
        KTCENLADTY

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  Fusarium oxysporum  IC50:  2.34 μg/ml  (1.99795 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Ng T.B.,Wong J.H.,
  •   Title:Gymnin, a potent defensin-like antifungal peptide from the Yunnan bean (Gymnocladus chinensis Baill).
  •   Journal:Peptides, 2003, 24, 963-968  [PubMed:14499273]

Comments

  •   Comments

    •     No comments found on LAMP database



CAPTCHA Image   Reload Image
Enter Code*: