Record in detail
General Info
- lamp_id:L01A000564
- Name:PA1C_RANPA
- FullName:Palustrin-1c
- Source:Rana palustris
- Mass:2875.5 Da
- Sequence Length:27 aa
- Isoelectric Point:10.63
- Activity:Antibacterial
- Sequence
ALSILRGLEKLAKMGIALTNCKATKKC - Function:Antimicrobial activity against Gram-negative bacterium E.coli. Possesses insulin-releasing activity.
Cross-Linking
- Cross-linking
- 1 Database:APD 616
- 2 Database:CAMP CAMPSQ1757
- 3 Database:DBAASP 2186
- 4 Database:dbAMP dbAMP_00364
- 5 Database:DRAMP DRAMP01228
- 6 Database:SATPdb satpdb14789
- 7 Database:Uniprot P84276
- 8 Database:AMD PAL1C_RANPA
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000564 From 1 To 27 E-value: 0.000000002 Score: 53.1
ALSILRGLEKLAKMGIALTNCKATKKC - 2. L01A000565 From 1 To 27 E-value: 0.000000005 Score: 51.6
ALSILKGLEKLAKMGIALTNCKATKKC - 3. L01A000562 From 3 To 28 E-value: 0.0001 Score: 37.4
FSILRGLKKLGKMGQAFVNCEIYKKC - 4. L01A000563 From 3 To 28 E-value: 0.0001 Score: 37
FSILRGLKKLGNMGQAFVNCKIYKKC - 5. L11A004386 From 4 To 37 E-value: 0.24 Score: 26.2
SIFRGVAKFASKGLGKKLAKLGVKLVACKISKQC
Activity
- Antibacterial Activities
- 1 Target: E.coli MIC: 80.51 μg/ml (27.9986 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Conlon J.M.,Dulka J.,Knoop F.C.,Basir Y.J.,
- Title:Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris.
- Journal:Biochim. Biophys. Acta, 2000, 1543, 95-105 [PubMed:11087945]
- [2] Shaw C.,McClean S.,Orr D.F.,Flatt P.R.,Marenah L.,
- Title:Brevinin-1 and multiple insulin-releasing peptides in the skin of the frog Rana palustris.
- Journal:J. Endocrinol., 2004, 181, 347-354 [PubMed:15128283]
- [3] Walker B.,Chen T.,Owens D.E.,Wang L.,Zhou M.,
- Title:Rapid identification of precursor cDNAs encoding five structural classes of antimicrobial peptides from pickerel frog (Rana palustris) skin secretion by single step "shotgun" cloning.
- Journal:Peptides, 2007, 28, 1605-1610 [PubMed:17698247]
Comments
- Comments
No comments found on LAMP database