Record in detail


General Info

  • lamp_id:L01A000567
  • Name:PA2B_RANPA
  • FullName:Palustrin-2b
  • Source:Rana palustris
  • Mass:3188.7 Da
  • Sequence Length:31 aa
  • Isoelectric Point:9.67
  • Activity:Antibacterial
  • Sequence
        GFFSTVKNLATNVAGTVIDTLKCKVTGGCRS
  • Function:Antimicrobial activity against Gram-negative bacterium E.coli.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000567    From 1 To 31 E-value: 0.000000000002 Score: 62.4
        GFFSTVKNLATNVAGTVIDTLKCKVTGGCRS
  • 2. L12A00999|    From 14 To 44 E-value: 0.000000000008 Score: 60.8
        GFLSTVKNLATNVAGTVIDTLKCKVTGGCRT
  • 3. L01A000568    From 1 To 31 E-value: 0.000000000008 Score: 60.8
        GFLSTVKNLATNVAGTVIDTLKCKVTGGCRS
  • 4. L01A000566    From 1 To 31 E-value: 0.0000000002 Score: 56.6
        GFLSTVKNLATNVAGTVLDTIRCKVTGGCRP
  • 5. L01A002397    From 1 To 29 E-value: 0.0000000003 Score: 55.5
        GFLSTVKNLATNVAGTVIDTIKCKVTGGC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_2    Interpro Link:IPR012521
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  E.coli  MIC:  248.72 μg/ml  (78.0004 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Conlon J.M.,Dulka J.,Knoop F.C.,Basir Y.J.,
  •   Title:Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris.
  •   Journal:Biochim. Biophys. Acta, 2000, 1543, 95-105  [PubMed:11087945]
  •   [2]  Blouin M.S.,Tennessen J.A.,
  •   Title:A revised leopard frog phylogeny allows a more detailed examination of adaptive evolution at ranatuerin-2 antimicrobial peptide loci.
  •   Journal:Immunogenetics, 2010, 62, 333-343  [PubMed:20179920]

Comments

  •   Comments

    •     No comments found on LAMP database



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