Record in detail
General Info
- lamp_id:L01A000582
- Name:AMP2_MELGA
- FullName:Antimicrobial peptide THP2
- Source:Meleagris gallopavo
- Mass:2302.8 Da
- Sequence Length:20 aa
- Isoelectric Point:9.82
- Activity:Antibacterial
- Sequence
LFCKRGTCHFGRCPSHLIKV - Function:Antibacterial activity against the Gram-positive bacterium Staphylococcus aureus. Lacks antibacterial activity against the Gram-negative bacterium E.coli K-12.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ543
- 2 Database:dbAMP dbAMP_05718
- 3 Database:SATPdb satpdb28655
- 4 Database:Uniprot P80392
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000255 From 29 To 48 E-value: 0.0000003 Score: 45.1
LFCKRGTCHFGRCPSHLIKV - 2. L01A000582 From 1 To 20 E-value: 0.0000006 Score: 44.3
LFCKRGTCHFGRCPSHLIKV - 3. L02A000267 From 1 To 20 E-value: 0.0000007 Score: 44.3
LFCKRGTCHFGRCPSHLIKV - 4. L12A09039| From 29 To 48 E-value: 0.0000009 Score: 43.9
LFCKRGSCHFGRCPSHLIKV - 5. L01A000067 From 1 To 19 E-value: 0.00001 Score: 40.4
LSCKRGTCHFGRCPSHLIK
Structure
- Domains
- 1 Name:Defensin_beta-typ Interpro Link:IPR001855
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Harmon B.G.,Wunderlich J.,Beach G.G.,Evans E.W.,
- Title:Isolation of antimicrobial peptides from avian heterophils.
- Journal:J. Leukoc. Biol., 1994, 56, 661-665 [MEDLINE:95053386]
- [2] Jackwood M.W.,Harmon B.G.,Brockus C.W.,
- Title:Characterization of beta-defensin prepropeptide mRNA from chicken and turkey bone marrow.
- Journal:Anim. Genet., 1998, 29, 283-289 [MEDLINE:98418188]
- [3] Lay J.O. Jr.,Liyanage R.,Rath N.C.,Kannan L.,
- Title:Direct screening identifies mature beta-defensin 2 in avian heterophils.
- Journal:Poult. Sci., 2009, 88, 372-379 [PubMed:19151352]
Comments
- Comments
No comments found on LAMP database