Record in detail

General Info

lamp_id:L01A000588
Name:XT2_XENTR
FullName:Antimicrobial peptide 2
Source:Xenopus tropicalis
Mass:2570.1 Da
Sequence Length:25 aa
Isoelectric Point:10.8
Activity:Antibacterial
Sequence
GVWSTVLGGLKKFAKGGLEAIVNPK
Function:Has very strong antibacterial activity against Gram-positive bacterium S.aureus and very weak activity against Gram-negative bacterium E.coli.

Cross-Linking

Cross-linking
1 Database:CAMP CAMPSQ548
2 Database:DBAASP 3155
3 Database:dbAMP dbAMP_04310
4 Database:DRAMP DRAMP02131
5 Database:SATPdb satpdb25259
6 Database:Uniprot P84382
7 Database:AMD XT2_XENTR

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000588 From 1 To 25 E-value: 0.00000001 Score: 50.4
GVWSTVLGGLKKFAKGGLEAIVNPK
2. L02A000425 From 1 To 25 E-value: 0.00000002 Score: 49.3
GCWSTVLGGLKKFAKGGLEAIVNPK
3. L13A010425 From 1 To 25 E-value: 0.00000003 Score: 48.9
GVWSTILGGLKKFAKGGLDAIVNPK
4. L13A021932 From 1 To 25 E-value: 0.0000001 Score: 47
GVWTTILGGLKKFAKGGLEALTNPK
5. L102704000 From 1 To 25 E-value: 0.000004 Score: 42
GFWSSALEGLKKFAKGGLEALTNPK

Structure

Domains

Structures

Activity

Antibacterial Activities
1 Target: E. coli MIC: 20.5608 μg/ml (8 μM)
2 Target: S. aureus MIC: 257.01 μg/ml (100 μM)

Toxicity

Toxicity

Reference

Reference
[1] Conlon J.M.,Knoop F.C.,Soto A.,Ali M.F.,
Title:Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae).
Journal:Biochim. Biophys. Acta, 2001, 1550, 81-89 [PubMed:11738090]

Comments

Comments