Record in detail


General Info

  • lamp_id:L01A000592
  • Name:XT6_XENTR
  • FullName:Antimicrobial peptide 6
  • Source:Xenopus tropicalis
  • Mass:1817.2 Da
  • Sequence Length:18 aa
  • Isoelectric Point:10.8
  • Activity:Antibacterial, Antifungal
  • Sequence
        GFLGSLLKTGLKVGSNLL
  • Function:Has antimicrobial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli and strong activity against yeast C.albicans. Enhances the antibacterial activity of XT3. Has strong hemolytic activity against human red blood cells.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000592    From 1 To 18 E-value: 0.0008 Score: 33.9
        GFLGSLLKTGLKVGSNLL
  • 2. L13A020168    From 1 To 17 E-value: 0.002 Score: 32.7
        GFLGSLLKTGLKVGSNL
  • 3. L13A011204    From 2 To 18 E-value: 0.012 Score: 30
        LLGSLLKTGLKVGSNLL
  • 4. L02A001901    From 5 To 21 E-value: 0.23 Score: 25.4
        FLGKALKAGLKIGSHLL
  • 5. L01A000587    From 1 To 18 E-value: 0.35 Score: 25
        GLLGPLLKIAAKVGSNLL

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  E. coli  MIC:  90.86 μg/ml  (50 μM)  
  •   2  Target:  S. aureus  MIC:  145.376 μg/ml  (80 μM)  

Toxicity

  •   Toxicity

Reference

  •   Reference
  •   [1]  Conlon J.M.,Knoop F.C.,Soto A.,Ali M.F.,
  •   Title:Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae).
  •   Journal:Biochim. Biophys. Acta, 2001, 1550, 81-89  [PubMed:11738090]

Comments

  •   Comments

    •     No comments found on LAMP database



CAPTCHA Image   Reload Image
Enter Code*: