Record in detail


General Info

  • lamp_id:L01A000597
  • Name:MAST_AGEPP
  • FullName:Agelaia-mastoparan
  • Source:Agelaia pallipes pallipes
  • Mass:1567.9 Da
  • Sequence Length:14 aa
  • Isoelectric Point:9.53
  • Activity:Antibacterial
  • Sequence
        INWLKLGKAIIDAL
  • Function:Hemolytic mast cell degranulator, presenting no antimicrobial action and no chemotaxis for polymorphonucleated leukocytes (PMNL).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000597    From 1 To 14 E-value: 0.014 Score: 29.3
        INWLKLGKAIIDAL
  • 2. L13A010919    From 1 To 13 E-value: 0.035 Score: 28.1
        INWLKLGKAIIDA
  • 3. L13A013782    From 1 To 14 E-value: 0.06 Score: 27.3
        INWLKLGKMVIDAL
  • 4. L02A001640    From 1 To 14 E-value: 0.18 Score: 25.4
        IDWLKLGKMVIDAL
  • 5. L13A021223    From 1 To 13 E-value: 0.46 Score: 24.3
        IDWLKLGKMVIDA

Structure

  •   Domains
  •   1  Name:Mastoparan_peptide    Interpro Link:IPR013214
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  E. coli  MIC:  382 μg/ml  (243.638 μM)  
  •   2  Target:  P.aeruginosa  MIC:  257 μg/ml  (163.914 μM)  
  •   3  Target:  B. subtilis  MIC:  237 μg/ml  (151.158 μM)  
  •   4  Target:  S.aureus  MIC:  191 μg/ml  (121.819 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Palma M.S.,Marques M.R.,de Souza B.M.,Mendes M.A.,
  •   Title:Structural and biological characterization of two novel peptides from the venom of the neotropical social wasp Agelaia pallipes pallipes.
  •   Journal:Toxicon, 2004, 44, 67-74  [PubMed:15225564]
  •   [2]  Palma M.S.,Delazari dos Santos L.,Monson de Souza B.,Mendes M.A.,
  •   Title:Structural characterization of novel chemotactic and mastoparan peptides from the venom of the social wasp Agelaiapallipes pallipes by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
  •   Journal:Rapid Commun. Mass Spectrom., 2004, 18, 636-642  [PubMed:15052574]

Comments

  •   Comments

    •     No comments found on LAMP database



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