Record in detail
General Info
- lamp_id:L01A000608
- Name:2SS1_BRARC
- FullName:Antibacterial napin
- Source:Brassica rapa subsp. chinensis
- Mass:2296.7 Da
- Sequence Length:20 aa
- Isoelectric Point:12.51
- Activity:Antibacterial
- Sequence
PAQPFRFPKHPQGPQTRPPI - Function:The small, basic, water-soluble napins are one of the two major kinds of storage proteins synthesized in the seed during its maturation. Inhibits cell-free protein synthesis. Has antibacterial activity against Gram-negative bacterium P.fluorescens, and the Gram-positive bacteria B.subtilis, B.cereus, B.megaterium and M.phei. No antibacterial activity against the Gram-positive bacterium S.aureus or the Gram-negative bacteria E.coli, E.aerogenes and P.aeruginosa.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ568
- 2 Database:dbAMP dbAMP_09865
- 3 Database:DRAMP DRAMP03467
- 4 Database:SATPdb satpdb23516
- 5 Database:Uniprot P84529
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000608 From 1 To 20 E-value: 0.000007 Score: 40.8
PAQPFRFPKHPQGPQTRPPI - 2. L13A014793 From 1 To 10 E-value: 0.95 Score: 23.9
PAQPFRFPKH - 3. L13A014679 From 1 To 10 E-value: 2.3 Score: 22.3
PQGPQTRPPI
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: Bacillus subtilis MIC: 236 μg/ml (102.756 μM)
- 2 Target: Bacillus cereus MIC: 222 μg/ml (96.6604 μM)
- 3 Target: Bacillus megaterium MIC: 15.62 μg/ml (6.80106 μM)
- 4 Target: M.phei MIC: 146 μg/ml (63.5695 μM)
- 5 Target: P.fluorescens MIC: 66 μg/ml (28.7369 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Ng T.B.,Ngai P.H.K.,
- Title:A napin-like polypeptide from dwarf Chinese white cabbage seeds with translation-inhibitory, trypsin-inhibitory, and antibacterial activities.
- Journal:Peptides, 2004, 25, 171-176 [PubMed:15062997]
Comments
- Comments
No comments found on LAMP database