Record in detail
General Info
- lamp_id:L01A000643
- Name:BR2EF_RANES
- FullName:Brevinin-2Ef
- Source:Rana esculenta
- Mass:3367 Da
- Sequence Length:33 aa
- Isoelectric Point:10.23
- Activity:Antibacterial
- Sequence
GIMDTLKNLAKTAGKGALQSLVKMASCKLSGQC - Function:Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species, and hemolytic activity.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1763
- 2 Database:dbAMP dbAMP_03113
- 3 Database:DRAMP DRAMP01933
- 4 Database:SATPdb satpdb27563
- 5 Database:Uniprot P40842
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000122 From 42 To 74 E-value: 0.0000000000001 Score: 66.6
GIMDTLKNLAKTAGKGALQSLVKMASCKLSGQC - 2. L01A000643 From 1 To 33 E-value: 0.0000000000003 Score: 65.5
GIMDTLKNLAKTAGKGALQSLVKMASCKLSGQC - 3. L01A000640 From 1 To 33 E-value: 0.000000000004 Score: 62
GILDTLKNLAKTAGKGALQGLVKMASCKLSGQC - 4. L01A003319 From 1 To 33 E-value: 0.00000000001 Score: 60.1
GIMDTLKNLAKTAGKGALQSLLNHASCKLSGQC - 5. L01A000488 From 1 To 33 E-value: 0.00000000002 Score: 59.3
GIMDTLKNLAKTAGKGALQSLLNKASCKLSGQC
Activity
- Antibacterial Activities
- 1 Target: E.coli D21 MIC: 1.68 μg/ml (0.49896 μM)
- 2 Target: B.megaterium BmII MIC: 0.67 μg/ml (0.19899 μM)
- 3 Target: S.aureus Cowan 1 MIC: 6.73 μg/ml (1.99881 μM)
- 4 Target: P.aeruginosa ATCC15692 MIC: 101.01 μg/ml (30 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Bossa F.,Barra D.,Mignogna G.,Simmaco M.,
- Title:Antimicrobial peptides from skin secretions of Rana esculenta. Molecular cloning of cDNAs encoding esculentin and brevinins and isolation of new active peptides.
- Journal:J. Biol. Chem., 1994, 269, 11956-11961 [MEDLINE:94216303]
Comments
- Comments
No comments found on LAMP database