Record in detail

lamp_id:L01A000646
Name:ES2A_RANES
FullName:Esculentin-2A
Source:Rana esculenta
Mass:3713.6 Da
Sequence Length:37 aa
Isoelectric Point:10.41
Activity:Antibacterial
Sequence
GILSLVKGVAKLAGKGLAKEGGKFGLELIACKIAKQC
Function:Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species, and hemolytic activity.

Top similar AMPs on LAMP
1. L01A000646 From 1 To 37 E-value: 0.00000000000006 Score: 67.8
GILSLVKGVAKLAGKGLAKEGGKFGLELIACKIAKQC
2. L01A000647 From 1 To 37 E-value: 0.0000000000004 Score: 65.1
GIFSLVKGAAKLAGKGLAKEGGKFGLELIACKIAKQC
3. L01A003348 From 1 To 37 E-value: 0.000000000007 Score: 60.8
GIFSLVKGVAKLAGKTLAKEGGKFGLELAMCKIAKQC
4. L01A003349 From 1 To 37 E-value: 0.0000000001 Score: 57
GILSLVKGAAKLLGKGLAKEGGKVGLEFIACKVTNQC
5. L01A003347 From 1 To 36 E-value: 0.0000000005 Score: 55.1
GILSLVK-VAKLAGKTFAKEGGKFGLEFIACKVTNQC

Antibacterial Activities
1 Target: E. coli D21 MIC: 1.49 μg/ml (0.401228 μM)
2 Target: B. megaterium BmII MIC: 0.74 μg/ml (0.199268 μM)
3 Target: S. aureus Cowan 1 MIC: 2.97 μg/ml (0.799763 μM)
4 Target: P.aeruginosa ATCC15692 MIC: 13 μg/ml (3.50065 μM)

Reference
[1] Bossa F.,Barra D.,Mignogna G.,Simmaco M.,
Title:Antimicrobial peptides from skin secretions of Rana esculenta. Molecular cloning of cDNAs encoding esculentin and brevinins and isolation of new active peptides.
Journal:J. Biol. Chem., 1994, 269, 11956-11961 [MEDLINE:94216303]