Record in detail


General Info

  • lamp_id:L01A000656
  • Name:IXCI_BOOMI
  • FullName:Chymotrypsin-elastase inhibitor ixodidin
  • Source:Boophilus microplus
  • Mass:7129.1 Da
  • Sequence Length:65 aa
  • Isoelectric Point:9.14
  • Activity:Antibacterial
  • Sequence
        QRGSRGQRCGPGEVFNQCGSACPRVCGRPPAQACTLQCVSGCFCRRGYIRTQRGGCIPERQCHQR
  • Function:Inhibits chymotrypsin and elastase. Has antibacterial activity against Gram-positive bacterium M.luteus and the Gram-negative bacterium E.coli.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000656    From 1 To 65 E-value: 3e-31 Score: 125
        QRGSRGQRCGPGEVFNQCGSACPRVCGRPPAQACTLQCVSGCFCRRGYIRTQRGGCIPERQCHQR
  • 2. L02A001157    From 1 To 65 E-value: 6e-31 Score: 124
        ERGSRGQRCGPGEVFNQCGSACPRVCGRPPAQACTLQCVSGCFCRRGYIRTQRGGCIPERQCHQR
  • 3. L11A001821    From 2 To 65 E-value: 1e-30 Score: 123
        RGSRGQRCGPGEVFNQCGSACPRVCGRPPAQACTLQCVSGCFCRRGYIRTQRGGCIPERQCHQR
  • 4. L13A012493    From 1 To 50 E-value: 7e-23 Score: 97.8
        QRGSRGQRCGPGEVFNQCGSACPRVCGRPPAQACTLQCVSGCFCRRGYIR
  • 5. L13A015204    From 1 To 50 E-value: 1e-22 Score: 97.1
        ERGSRGQRCGPGEVFNQCGSACPRVCGRPPAQACTLQCVSGCFCRRGYIR

Structure

  •   Domains
  •   1  Name:TIL_dom    Interpro Link:IPR002919
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  Micrococcus luteus  MIC:  0.12 μg/ml  (0.0168324 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Bulet P.,Tanaka A.S.,Eberlin M.N.,Almeida I.C.,Fogaca A.C.,
  •   Title:Ixodidin, a novel antimicrobial peptide from the hemocytes of the cattle tick Boophilus microplus with inhibitory activity against serine proteinases.
  •   Journal:Peptides, 2006, 27, 667-674  [PubMed:16191451]

Comments

  •   Comments

    •     No comments found on LAMP database



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