Record in detail


General Info

  • lamp_id:L01A000658
  • Name:GLL1A_CHICK
  • FullName:Gallinacin-1 alpha
  • Source:Gallus gallus
  • Mass:4587.5 Da
  • Sequence Length:39 aa
  • Isoelectric Point:10.03
  • Activity:Antibacterial, Antifungal
  • Sequence
        GRKSDCFRKNGFCAFLKCPYLTLISGKCSRFHLCCKRIW
  • Function:Has bactericidal activity. Potent activity against E.coli ML-35, L.monocytogenes EGD and C.albicans.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A09054|    From 26 To 64 E-value: 1e-18 Score: 83.6
        GRKSDCFRKNGFCAFLKCPYLTLISGKCSRFHLCCKRIW
  • 2. L01A000658    From 1 To 39 E-value: 6e-18 Score: 81.3
        GRKSDCFRKNGFCAFLKCPYLTLISGKCSRFHLCCKRIW
  • 3. L12A09056|    From 26 To 64 E-value: 3e-17 Score: 79
        GRKSDCFRKSGFCASLKCPYLTLISGKCSRFHLCCKRIW
  • 4. L03A000259    From 26 To 64 E-value: 1e-16 Score: 76.6
        GRKSDCFRKSGFCAFLKCPSLTLISGKCSRFYLCCKRIW
  • 5. L01A000595    From 1 To 39 E-value: 6e-16 Score: 74.7
        GRKSDCFRKSGFCAFLKCPSLTLISGKCSRFYLCCKRIW

Structure

  •   Domains
  •   1  Name:Defensin_beta-typ    Interpro Link:IPR001855
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Lee T.D.,Tan L.,Kokryakov V.N.,Swiderek K.M.,Harwig S.S.L.,
  •   Title:Gallinacins: cysteine-rich antimicrobial peptides of chicken leukocytes.
  •   Journal:FEBS Lett., 1994, 342, 281-285  [MEDLINE:94200386]
  •   [2]  Harmon B.G.,Wunderlich J.,Beach G.G.,Evans E.W.,
  •   Title:Isolation of antimicrobial peptides from avian heterophils.
  •   Journal:J. Leukoc. Biol., 1994, 56, 661-665  [MEDLINE:95053386]
  •   [3]  Brogden K.A.,Sacco R.E.,Liu L.,Nguyen T.,Zhao C.,
  •   Title:Gallinacin-3, an inducible epithelial beta-defensin in the chicken.
  •   Journal:Infect. Immun., 2001, 69, 2684-2691  [MEDLINE:21153640]

Comments

  •   Comments

    •     No comments found on LAMP database



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