Record in detail
General Info
- lamp_id:L01A000659
- Name:GLL1A_CHICK
- FullName:Gallinacin-1 alpha
- Source:Gallus gallus
- Mass:3786.5 Da
- Sequence Length:34 aa
- Isoelectric Point:8.8
- Activity:Antibacterial
- Sequence
GRKSDCFRKNGFCAFLKCPYLTLISGLCSXFHLC - Function:Has bactericidal activity. Potent activity against E.coli ML-35, L.monocytogenes EGD and C.albicans.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ619
- 2 Database:dbAMP dbAMP_03995
- 3 Database:Uniprot P46157
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000659 From 1 To 34 E-value: 0.00000000000004 Score: 68.6
GRKSDCFRKNGFCAFLKCPYLTLISGLCSXFHLC - 2. L12A09054| From 26 To 59 E-value: 0.00000000000006 Score: 67.8
GRKSDCFRKNGFCAFLKCPYLTLISGKCSRFHLC - 3. L01A000658 From 1 To 34 E-value: 0.0000000000002 Score: 66.2
GRKSDCFRKNGFCAFLKCPYLTLISGKCSRFHLC - 4. L02A000265 From 1 To 33 E-value: 0.0000000000008 Score: 64.3
GRKSDCFRKNGFCAFLKCPYLTLISGLCS-FHLC - 5. L12A09056| From 26 To 59 E-value: 0.000000000001 Score: 63.5
GRKSDCFRKSGFCASLKCPYLTLISGKCSRFHLC
Structure
- Domains
- 1 Name:Defensin_beta-typ Interpro Link:IPR001855
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Lee T.D.,Tan L.,Kokryakov V.N.,Swiderek K.M.,Harwig S.S.L.,
- Title:Gallinacins: cysteine-rich antimicrobial peptides of chicken leukocytes.
- Journal:FEBS Lett., 1994, 342, 281-285 [MEDLINE:94200386]
- [2] Harmon B.G.,Wunderlich J.,Beach G.G.,Evans E.W.,
- Title:Isolation of antimicrobial peptides from avian heterophils.
- Journal:J. Leukoc. Biol., 1994, 56, 661-665 [MEDLINE:95053386]
- [3] Brogden K.A.,Sacco R.E.,Liu L.,Nguyen T.,Zhao C.,
- Title:Gallinacin-3, an inducible epithelial beta-defensin in the chicken.
- Journal:Infect. Immun., 2001, 69, 2684-2691 [MEDLINE:21153640]
Comments
- Comments
No comments found on LAMP database