Record in detail


General Info

  • lamp_id:L01A000662
  • Name:KB1_MESMA
  • FullName:Peptide BmKb1
  • Source:Mesobuthus martensii
  • Mass:1911.3 Da
  • Sequence Length:18 aa
  • Isoelectric Point:9.69
  • Activity:Antibacterial
  • Sequence
        FLFSLIPSAISGLISAFK
  • Function:Has antibacterial activity against Gram-positive bacteria S.aureus, M.luteus, B.subtilis, and Gram-negative bacteria E.coli, and P.aeruginosa.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A002659    From 23 To 40 E-value: 0.0001 Score: 36.2
        FLFSLIPSAISGLISAFK
  • 2. L01A002660    From 23 To 40 E-value: 0.0002 Score: 36.2
        FLFSLIPSAISGLISAFK
  • 3. L12A06729|    From 23 To 40 E-value: 0.0002 Score: 36.2
        FLFSLIPSAISGLISAFK
  • 4. L12A12358|    From 1 To 18 E-value: 0.0003 Score: 35.4
        FLFSLIPSAISGLISAFK
  • 5. L13A027527    From 1 To 18 E-value: 0.0003 Score: 35
        FLFSLIPSAISGLISAFK

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  S.aureus  MIC:  16 μg/ml  (8.37127 μM)  
  •   2  Target:  M.luteus  MIC:  81.5 μg/ml  (42.6411 μM)  
  •   3  Target:  B.subtilis  MIC:  48.8 μg/ml  (25.5324 μM)  
  •   4  Target:  E.coli  MIC:  18.1 μg/ml  (9.46999 μM)  
  •   5  Target:  P.aeruginosa  MIC:  90.8 μg/ml  (47.5069 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Li W.-X.,Zhu S.-Y.,Zhu Y.,Wang S.-X.,Zeng X.-C.,
  •   Title:Identification and functional characterization of novel scorpion venom peptides with no disulfide bridge from Buthus martensii Karsch.
  •   Journal:Peptides, 2004, 25, 143-150  [PubMed:15062994]
  •   [2]  Liu H.,Cao Z.-J.,Hahin R.,Zeng X.-C.,Luo F.,
  •   Title:Genomic organization of four novel nondisulfide-bridged peptides from scorpion Mesobuthus martensii Karsch: gaining insight into evolutionary mechanism.
  •   Journal:Peptides, 2005, 26, 2427-2433  [PubMed:16040157]

Comments

  •   Comments

    •     No comments found on LAMP database



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