Record in detail

General Info

lamp_id:L01A000663
Name:DEFN_ARCDE
FullName:Defensin ARD1
Source:Archaeoprepona demophon
Mass:4803.4 Da
Sequence Length:44 aa
Isoelectric Point:8.12
Activity:Antifungal
Sequence
DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFANVNCWCET
Function:Possesses potent anti-fungal activity.

Cross-Linking

Cross-linking
1 Database:CAMP CAMPSQ623
2 Database:DBAASP 2089
3 Database:dbAMP dbAMP_01102
4 Database:DRAMP DRAMP03063
5 Database:SATPdb satpdb16149
6 Database:Uniprot P84156
7 Database:DEF DEF126

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000663 From 1 To 44 E-value: 4e-21 Score: 91.7
DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFANVNCWCET
2. L01A003216 From 1 To 44 E-value: 5e-21 Score: 91.3
DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFANINCWCET
3. L01A003209 From 1 To 44 E-value: 8e-21 Score: 90.9
DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFANVNCWCQT
4. L01A003214 From 1 To 44 E-value: 1e-20 Score: 90.1
DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFLNVNCWCET
5. L01A003215 From 1 To 44 E-value: 1e-20 Score: 90.1
DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFINVNCWCET

Structure

Domains
1 Name:Defensin_invertebrate/fungal Interpro Link:IPR001542
2 Name:Scorpion_toxinL/defesin Interpro Link:IPR002061

Structures

1
PDB:1OZZ
Method:NMR
Chains:A=1-44
2
PDB:1P00
Method:NMR
Chains:A=1-44
3
PDB:1P0A
Method:NMR
Chains:A=1-44

Activity

Antibacterial Activities

Toxicity

Toxicity

Reference

Reference
[1] Guenneugues M.,Menin L.,Legrain M.,Barbault F.,Landon C.,
Title:Lead optimization of antifungal peptides with 3D NMR structures analysis.
Journal:Protein Sci., 2004, 13, 703-713 [PubMed:14978308]

Comments

Comments