Record in detail

lamp_id:L01A000664
Name:P90683_ASCSU
FullName:
Source:Ascaris suum
Mass:7576.6 Da
Sequence Length:72 aa
Isoelectric Point:9.04
Activity:Antibacterial
Sequence
AVDFSSCARMDVPGLSKVAQGLCISSCKFQNCGTGHCEKRGGRPTCVCDRCGRGGGEWPSVPMPKGRSSRGR
Function:null

Top similar AMPs on LAMP
1. L03A000170 From 19 To 90 E-value: 4e-38 Score: 148
AVDFSSCARMDVPGLSKVAQGLCISSCKFQNCGTGHCEKRGGRPTCVCDRCGRGGGEWPSVPMPKGRSSRGR
2. L02A001523 From 1 To 72 E-value: 3e-37 Score: 145
AVDFSSCARMDVPGLSKVAQGLCISSCKFQNCGTGHCEKRGGRPTCVCDRCGRGGGEWPSVPMPKGRSSRGR
3. L01A000664 From 1 To 72 E-value: 4e-37 Score: 144
AVDFSSCARMDVPGLSKVAQGLCISSCKFQNCGTGHCEKRGGRPTCVCDRCGRGGGEWPSVPMPKGRSSRGR
4. L11A001319 From 1 To 71 E-value: 1e-36 Score: 143
AVDFSSCARMDVPGLSKVAQGLCISSCKFQNCGTGHCEKRGGRPTCVCDRCGRGGGEWPSVPMPKGRSSRG
5. L12A00699| From 1 To 53 E-value: 3e-26 Score: 108
AVDFSSCARMDVPGLSKVAQGLCISSCKFQNCGTGHCEKRGGRPTCVCDRCGR

Antibacterial Activities
1 Target: Escherichia coli JM109 IC50: 50 μg/ml (6.59927 μM)
2 Target: Proteus vulgaris ATCC 13315 IC50: 10 μg/ml (1.31985 μM)
3 Target: Staphylococcus aureus ATCC6538P IC50: 0.6 μg/ml (0.0791912 μM)
4 Target: Bacillus subtilis ATCC6633 IC50: 1.2 μg/ml (0.158382 μM)
5 Target: Micrococcus luteus ATCC398 IC50: 0.8 μg/ml (0.105588 μM)

Reference
[1] Komatsu S.,Kato Y.,
Title:ASABF, a novel cysteine-rich antibacterial peptide isolated from the nematode Ascaris suum. Purification, primary structure, and molecular cloning of cDNA.
Journal:J. Biol. Chem., 1996, 271, 30493-30498 [MEDLINE:97094782]
[2] Suzuki M.,Murakami R.,Aizawa T.,Yoshida S.,Zhang H.,
Title:In vitro antimicrobial properties of recombinant ASABF, an antimicrobial peptide isolated from the nematode Ascaris suum.
Journal:Antimicrob. Agents Chemother., 2000, 44, 2701-2705 [MEDLINE:20448739]
[3] Nitta K.,Kawano K.,Hoshino H.,Aizawa T.,Kato Y.,
Title:abf-1 and abf-2, ASABF-type antimicrobial peptide genes in Caenorhabditis elegans.
Journal:Biochem. J., 2002, 361, 221-230 [MEDLINE:21633952]