Record in detail

General Info

lamp_id:L01A000668
Name:CT12_LITCI
FullName:Citropin-1.2
Source:Litoria citropa
Mass:1616 Da
Sequence Length:16 aa
Isoelectric Point:9.53
Activity:Antibacterial,Anticancer
Sequence
GLFDIIKKVASVVGGL
Function:Bacteriostatic action for Gram-positive bacteria.

Cross-Linking

Cross-linking
1 Database:APD 352
2 Database:CAMP CAMPSQ628
3 Database:DBAASP 1321
4 Database:dbAMP dbAMP_03280
5 Database:DRAMP DRAMP01594
6 Database:SATPdb satpdb22932
7 Database:Uniprot P81840
8 Database:AMD CT12_LITCI

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000668 From 1 To 16 E-value: 0.003 Score: 31.6
GLFDIIKKVASVVGGL
2. L01A000669 From 1 To 16 E-value: 0.004 Score: 31.2
GLFDIIKKVASVIGGL
3. L01A000667 From 1 To 16 E-value: 0.007 Score: 30.4
GLFDVIKKVASVIGGL
4. L13A017225 From 1 To 15 E-value: 0.009 Score: 30
GLFDIIKKVASVVGG
5. L13A019211 From 1 To 15 E-value: 0.012 Score: 29.6
GLFDIIKKVASVIGG

Structure

Domains
1 Name:Aurein_antimicrobial_peptide Interpro Link:IPR013157

Structures

Activity

Antibacterial Activities
1 Target: Bacillus cereus MIC: 25 μg/ml (15.4703 μM)
2 Target: Leuconostoc lactis MIC: 3 μg/ml (1.85644 μM)
3 Target: Listeria innocua MIC: 100 μg/ml (61.8812 μM)
4 Target: Micrococcus luteus MIC: 12 μg/ml (7.42574 μM)
5 Target: Staphylococcus aureus MIC: 25 μg/ml (15.4703 μM)
6 Target: Staphylococcus epidermidis MIC: 25 μg/ml (15.4703 μM)
7 Target: Streptococcus uberis MIC: 12 μg/ml (7.42574 μM)
8 Target: S. aureus MIC: 25.048 μg/ml (15.5 μM)

Toxicity

Toxicity

Reference

Reference
[1] Chia B.C.S.,Bowie J.H.,Carver J.A.,Wabnitz P.A.,Wegener K.L.,
Title:Host defence peptides from the skin glands of the Australian blue mountains tree-frog Litoria citropa. Solution structure of the antibacterial peptide citropin 1.1.
Journal:Eur. J. Biochem., 1999, 265, 627-637 [MEDLINE:99435977]

Comments

Comments