Record in detail

General Info

lamp_id:L01A000669
Name:CT13_LITCI
FullName:Citropin-1.3
Source:Litoria citropa
Mass:1630 Da
Sequence Length:16 aa
Isoelectric Point:9.53
Activity:Antibacterial,Anticancer
Sequence
GLFDIIKKVASVIGGL
Function:Bacteriostatic action for Gram-positive bacteria.

Cross-Linking

Cross-linking
1 Database:APD 353
2 Database:CAMP CAMPSQ629
3 Database:DBAASP 1322
4 Database:dbAMP dbAMP_03279
5 Database:DRAMP DRAMP01600
6 Database:SATPdb satpdb15856
7 Database:Uniprot P81846

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000669 From 1 To 16 E-value: 0.003 Score: 31.6
GLFDIIKKVASVIGGL
2. L01A000667 From 1 To 16 E-value: 0.004 Score: 31.2
GLFDVIKKVASVIGGL
3. L01A000668 From 1 To 16 E-value: 0.004 Score: 31.2
GLFDIIKKVASVVGGL
4. L13A019211 From 1 To 15 E-value: 0.009 Score: 30
GLFDIIKKVASVIGG
5. L13A020458 From 1 To 16 E-value: 0.01 Score: 30
GLFDVIKKVAAVIGGL

Structure

Domains
1 Name:Aurein_antimicrobial_peptide Interpro Link:IPR013157

Structures

Activity

Antibacterial Activities
1 Target: Bacillus cereus MIC: 25 μg/ml (15.3374 μM)
2 Target: Leuconostoc lactis MIC: 6 μg/ml (3.68098 μM)
3 Target: Listeria innocua MIC: 25 μg/ml (15.3374 μM)
4 Target: Micrococcus luteus MIC: 12 μg/ml (7.36196 μM)
5 Target: Staphylococcus aureus MIC: 25 μg/ml (15.3374 μM)
6 Target: Staphylococcus epidermidis MIC: 25 μg/ml (15.3374 μM)
7 Target: Streptococcus uberis MIC: 12 μg/ml (7.36196 μM)
8 Target: S. aureus MIC: 25.0368 μg/ml (15.36 μM)

Toxicity

Toxicity

Reference

Reference
[1] Chia B.C.S.,Bowie J.H.,Carver J.A.,Wabnitz P.A.,Wegener K.L.,
Title:Host defence peptides from the skin glands of the Australian blue mountains tree-frog Litoria citropa. Solution structure of the antibacterial peptide citropin 1.1.
Journal:Eur. J. Biochem., 1999, 265, 627-637 [MEDLINE:99435977]

Comments

Comments