Record in detail


General Info

  • lamp_id:L01A000691
  • Name:JELL3_APIME
  • FullName:Jellein-3
  • Source:Apis mellifera
  • Mass:1083.3 Da
  • Sequence Length:9 aa
  • Isoelectric Point:7.55
  • Activity:Antibacterial
  • Sequence
        EPFKISIHL
  • Function:Has antibacterial activity against the Gram-positive bacteria S.aureus ATCC 6535 and S.saprophyticus, and the Gram-negative bacteria E.coli CCT1371, E.cloacae ATCC 23355, K.pneumoniae ATCC 13883 and P.aeruginosa ATCC 27853, and antifungal activity against C.albicans. Lacks cytolytic activity and do not induce rat peritoneal mast cell degranulation.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L11A007637    From 1 To 9 E-value: 1.5 Score: 21.9
        EPFKISIHL
  • 2. L01A000691    From 1 To 9 E-value: 1.8 Score: 21.6
        EPFKISIHL
  • 3. L02A001212    From 1 To 9 E-value: 5.2 Score: 20
        EPFKLSLHL
  • 4. L13A023686    From 1 To 8 E-value: 5.3 Score: 20
        EPFKISIH
  • 5. L11A007636    From 2 To 9 E-value: 5.4 Score: 20
        PFKISIHL

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  S.aureus  MIC:  30 μg/ml  (27.6932 μM)  
  •   2  Target:  S.saprophyticus  MIC:  30 μg/ml  (27.6932 μM)  
  •   3  Target:  E.coli  MIC:  15 μg/ml  (13.8466 μM)  
  •   4  Target:  P.aeruginosa  MIC:  30 μg/ml  (27.6932 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Cesar L.M.,Konno K.,de Souza B.M.,Mendes M.A.,Fontana R.,
  •   Title:Jelleines: a family of antimicrobial peptides from the royal jelly of honeybees (Apis mellifera).
  •   Journal:Peptides, 2004, 25, 919-928  [PubMed:15203237]

Comments

  •   Comments

    •     No comments found on LAMP database



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